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Nihal Abdalla Ibrahim
- Assistant Professor
- Ext: 6265
Dr. Nihal Abdalla Ibrahim is a clinician and physiologist. She earned her MBBCh, MSc, and PhD from the Faculty of Medicine with Excellent degrees and Honor's Awards. Her Master's degree was in Medical Clinical Physiology, with a concentration in Clinical Pharmacology and Clinical Biochemistry. Dr. Nihal's PhD research focused on the recently discovered hormone, Ghrelin, and its relation to appetite, diabetes, obesity, and the metabolism of various types of macronutrients. She earned her PhD in Medical Clinical Physiology, and her thesis was accepted with Excellent grades. She also passed all the written, oral, clinical, and practical examinations for the Doctorate degree with Excellent grades. Dr. Nihal has practiced medicine as an internist in Egypt and Dubai, UAE. She has also taught Medical Physiology at the Faculty of Medicine. Currently, she teaches Anatomy and Physiology at the College of Pharmacy and Health Sciences and in the Biomedical Engineering Department at Ajman University. Dr. Nihal has several impactful publications in high-quality journals and prestigious conferences. She is the Head of the Events Committee at the College of Pharmacy and Health Sciences and is a member of various committees at both the university and college levels.
Education
- PhD in Human Medical Physiology and Clinical Physiology, Faculty of Medicine, Alexandria University, Egypt, 2009.
- MSc in Medical Clinical Physiology (concentration in Clinical Pharmacology and Clinical Biochemistry) with Excellent degree and Honor's Award, Physiology Department, Faculty of Medicine, Tanta University, Egypt, 1990.
- MBBCh degree from the Faculty of Medicine, Cairo University, Egypt, with Excellent grade and Honor's Award, 1982.
- Certificate in Computer Software Courses from The Technical Institute, Dubai, Ministry of Education (License 2/440 - 1991), Dubai, UAE, 1996-1997.
PhD in Human Medical Physiology and Clinical Physiology, Faculty of Medicine, Alexandria University, Egypt, 2009.
MSc in Medical Clinical Physiology (concentration in Clinical Pharmacology and Clinical Biochemistry) with Excellent degree and Honor's Award, Physiology Department, Faculty of Medicine, Tanta University, Egypt, 1990.
MBBCh degree from the Faculty of Medicine, Cairo University, Egypt, with Excellent grade and Honor's Award, 1982.
Certificate in Computer Software Courses from The Technical Institute, Dubai, Ministry of Education (License 2/440 - 1991), Dubai, UAE, 1996-1997.
Experience
- Assistant Professor, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, 2014 – Present.
- Lecturer, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, UAE, 1998 – 2010.
- Researcher and Physician, Dubai Medical Center for Treatment and Research, Dubai, UAE, 1995 – 1998.
- Assistant Lecturer, Clinical Physiology Department, Faculty of Medicine, Tanta University, Egypt, 1991 – 1995.
- Demonstrator, Clinical Physiology Department, Faculty of Medicine, Tanta University, Egypt, 1987 – 1991.
- Resident Doctor, Internal Medicine and Pediatrics Departments, Students' Hospital, Faculty of Medicine, Alexandria University, Egypt, 1983 – 1987.
- Internship Trainee Doctor, Hospitals of the Faculty of Medicine, Cairo University, Egypt, 1982 – 1983.
Assistant Professor, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, 2014 – Present.
Lecturer, Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, UAE, 1998 – 2010.
Researcher and Physician, Dubai Medical Center for Treatment and Research, Dubai, UAE, 1995 – 1998.
Assistant Lecturer, Clinical Physiology Department, Faculty of Medicine, Tanta University, Egypt, 1991 – 1995.
Demonstrator, Clinical Physiology Department, Faculty of Medicine, Tanta University, Egypt, 1987 – 1991.
Resident Doctor, Internal Medicine and Pediatrics Departments, Students' Hospital, Faculty of Medicine, Alexandria University, Egypt, 1983 – 1987.
Internship Trainee Doctor, Hospitals of the Faculty of Medicine, Cairo University, Egypt, 1982 – 1983.
Teaching Area
- Anatomy and Physiology I and Anatomy and Physiology II for Pharmacy students. Responsibilities: Designing and updating all courses on Moodle. Using Interactive Anatomy and Physiology software. Developing and maintaining online course material (E-Learning, Moodle) with continuous updates. Including assignments and quizzes. Using the following innovative techniques and tools on Moodle: Turnitin assignments Educational videos and interactive techniques Visual and auditory approaches to explain the mechanisms of human physiology Computer simulations to describe various anatomy topics Clarifying difficult topics using Problem-Based Learning (PBL) approach Cases, quizzes, and crossword games Instructional Strategies to Enhance the Learning Process: Turnitin assignments Educational videos and interactive techniques Visual, auditory, and interactive approaches Discussions Computer simulations Problem-Based Learning (PBL) Assignments and student presentations
- Biology Course for Biomedical Engineering.
- Practical Anatomy and Physiology Courses for Pharmacy Students.
- Practical Anatomy Course for Biomedical Engineering.
- First Aid as a University Requirement Course.
- Fundamentals of Human Nutrition as a University Requirement Course.
- Clinical Physiology for Medical Students, College of Medicine, Tanta University.
- Human Medical Anatomy and Physiology
- Medical Physiology
- Human Anatomy for Biomedical Engineering
- Human Physiology for Biomedical Engineering
- Biology
- Pathology for Pharmacy students
Anatomy and Physiology I and Anatomy and Physiology II for Pharmacy students. Responsibilities: Designing and updating all courses on Moodle. Using Interactive Anatomy and Physiology software. Developing and maintaining online course material (E-Learning, Moodle) with continuous updates. Including assignments and quizzes. Using the following innovative techniques and tools on Moodle: Turnitin assignments Educational videos and interactive techniques Visual and auditory approaches to explain the mechanisms of human physiology Computer simulations to describe various anatomy topics Clarifying difficult topics using Problem-Based Learning (PBL) approach Cases, quizzes, and crossword games Instructional Strategies to Enhance the Learning Process: Turnitin assignments Educational videos and interactive techniques Visual, auditory, and interactive approaches Discussions Computer simulations Problem-Based Learning (PBL) Assignments and student presentations
Biology Course for Biomedical Engineering.
Practical Anatomy and Physiology Courses for Pharmacy Students.
Practical Anatomy Course for Biomedical Engineering.
First Aid as a University Requirement Course.
Fundamentals of Human Nutrition as a University Requirement Course.
Clinical Physiology for Medical Students, College of Medicine, Tanta University.
Human Medical Anatomy and Physiology
Medical Physiology
Human Anatomy for Biomedical Engineering
Human Physiology for Biomedical Engineering
Biology
Pathology for Pharmacy students
Research
- Vitamin D and Metabolism. • The Role of Vitamin D deficiency in various pathophysiological aspects of metabolism.
- Leptin Hormone and Obesity. The Impact Of Apelin Ligand Binding On APJ Receptor on the Various Physiological And Pathophysiological Aspects Of Metabolism and Homeostasis.
- Cytokines and Diabetes: The Role of the Cytokine Visfatin in Diabetic Neuropathy.
- Ghrelin Hormone and Diabetes: Correlation Between Fasting Serum Ghrelin Level, Insulin, and Leptin in Type 1 Diabetes.
- Pharmacological effects of different herbs.
- Metabolic effects of Lagocephalus Scleratus toxins.
- Variation in Serum and Salivary secretion composition due to various toxins.
- Effect of C. cerastus injection on chemical composition of blood and saliva.
- Drug adherence
- Gerentology
- Obesity
- Metabolic syndrome
- Nanomedicine: The Potential of Nanocarrier-Based Drug Delivery Systems for Brain Targeting – A Current Review of the Literature.
- Vaccines: Recent Strategies Driving Oral Biologic Administration.
- Pharmacovigilance. An Exploration of Knowledge, Attitude, and Practices of Physicians toward Pharmacovigilance at Tertiary Care Hospitals in Khyber-Pakhtunkhwa Province, Pakistan
- Skin Cancer: Awareness of Pharmacists and Consumers Regarding the Protective Effects of Sunscreens Against Skin Cancer.
Vitamin D and Metabolism. • The Role of Vitamin D deficiency in various pathophysiological aspects of metabolism.
Leptin Hormone and Obesity. The Impact Of Apelin Ligand Binding On APJ Receptor on the Various Physiological And Pathophysiological Aspects Of Metabolism and Homeostasis.
Cytokines and Diabetes: The Role of the Cytokine Visfatin in Diabetic Neuropathy.
Ghrelin Hormone and Diabetes: Correlation Between Fasting Serum Ghrelin Level, Insulin, and Leptin in Type 1 Diabetes.
Pharmacological effects of different herbs.
Metabolic effects of Lagocephalus Scleratus toxins.
Variation in Serum and Salivary secretion composition due to various toxins.
Effect of C. cerastus injection on chemical composition of blood and saliva.
Drug adherence
Gerentology
Obesity
Metabolic syndrome
Nanomedicine: The Potential of Nanocarrier-Based Drug Delivery Systems for Brain Targeting – A Current Review of the Literature.
Vaccines: Recent Strategies Driving Oral Biologic Administration.
Pharmacovigilance. An Exploration of Knowledge, Attitude, and Practices of Physicians toward Pharmacovigilance at Tertiary Care Hospitals in Khyber-Pakhtunkhwa Province, Pakistan
Skin Cancer: Awareness of Pharmacists and Consumers Regarding the Protective Effects of Sunscreens Against Skin Cancer.
Publications
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Nihal Abdalla Ibrahim*, The Impact Of Apelin Ligand Binding On APJ Receptor on the Various Physiological And Pathophysiological Aspects Of Metabolism and Homeostasis. Europ J. of Pharm. And Med. Res., 2017,4 (01), 61-69. ISSN 2394-3211 EJPMR Impact Factor 3.628
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Ahmed Gaili, Sundos Qasim, Zakia Metwali , Nihal Abdalla and Sara Al –Akshar The Relationship Between Knowledge and Drug Adherence in Hypertensive Patients: A Cross Sectional Study in UAE. A J A D D [4][01][2016]001-011 American Journal of Advanced Drug Delivery, www.ojadd.com, ISSN 2321-547X.
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Ibrahim Nihal A*, A Effect of High Fat Diet and High Protein Diet on Fasting Serum Ghrelin Level in Type-1 Diabetes International Research Journal of Medical Sciences. ISSN 2320 –7353 Vol. 3(6), 5-14, June (2015) Int. Res. J. Medical Sci. International Science Congress Association
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Farajallah A , Abdalla N, Ahmed A , Abusnena S. The Relationship between Type 2 Diabetes and Total Ghrelin Level in a Population Sample in the United Arab Emirates. IOSR Journal Of Pharmacy (e)-ISSN: 2250-3013, (p)-ISSN: 2319-4219 www.iosrphr.org Volume 4, Issue 6 (June 2014), PP. 01-08 1
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Metwalli Z, Abdalla N* , El Barrani R. A Natural Alternative to Conventional Antibiotics. Res J Ph B Ch Sc. 2014 RJPBCS, ISSN: 0975-8585 July - August 2014, 5(4) , PP. 588-599
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El Serougy M, Nihal A, Salma N, Madi M. Effect of crude toxin extracted from the Red Sea fish Lagocephalus Scleratus on salivary secretion in dogs. Bulletin of Egyptian Society of Physiological Sciences, 1992 March, 12(2), P. 101
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Nihal A, El Serougy M, Salma N, Madi M. Effect of crude toxin extracted from the Red Sea fish Lagocephalus Scleratus on some aspects of carbohydrates and lipids metabolism in anesthetized dogs. Bulletin of Egyptian Society of Physiological Sciences, 1992 March, 12(2), P. 65.
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Ebtesam Khalil, Nihal A. Ibrahim, Maher Al Shayeb, Syed Kuduruthullah, Mawada Hassan, Stress-related Oral manifestations disorders in a population sample of patients attending Ajman University dental clinics.Journal of International Dental and Medical Research,2020, 13(1)
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Ibrahim NA*, Nabil N, Ghaleb S. Pathophysiology of the risk factors associated with osteoporosis and their correlation to the T-score value in patients with osteopenia and osteoporosis in the United Arab Emirates. J Pharm Bioall Sci 2019;11:364-72
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Ibrahim NA*, Edis Z, Al Owais KS, Adherence of Geriatric patients and their beliefs Towards their medicines in the United Arab Emirates. J Pharm Bioall Sci. ,2020;12:22-300
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Nihal Abdalla Ibrahim *, Zehra Edis, Klaithem Salem Al-Owais, ROLE OF PHYSICIANS IN DRUG ADHERENCE OF GERIATRIC PATIENTS IN THE UNITED ARAB EMIRATES. Int. Res. J. Pharm. 2018, 9 (9)
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Nihal Abdalla Ibrahim, Nada Mohamed Saleh, Fatima Koprulu* , Altaf Hani Abdulrahim ;Metabolic syndrome associated risk factors: Findings among female university students in the United Arab Emirates. J pharmacy and Pharmaceutical Sciences. Accepted. in press
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Nurses’ Perception regarding Pharmaceutical Care Practice: a Qualitative Approach, Tropical Journal of Pharmaceutical Research, Accepted
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Exploring Community Pharmacists’ Perception towards Responsible Provision of Patient Care Services : A Quantitative Assessment. Tropical Journal of Pharmaceutical Research. Accepted
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Stress‑Related Oral Manifestations Disorders in A Population Sample of Patients Attending Ajman University Dental Clinics
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Thyroid cancer risk factors and Pakistani University students’ awareness towards its preventive practice
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Recent strategies driving oral biologic administration
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Potential of Nanocarrier-Based Drug Delivery Systems for Brain Targeting: A Current Review of Literature
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Mechanistic Investigations of Ellagic Acid via Topological and Functional Analysis of its Protein Interaction Network LATIN AMERICAN JOURNAL OF PHARMACY 40 (6), 1273-1280
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In Silico Prediction of the Mechanism of Radix Paeoniae Rubra against Menstruation Disorder
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An exploration of knowledge, attitude, and practices of physicians towards pharmacovigilance at tertiary care hospitals in Khyber-Pakhtunkhwa province, Pakistan
-
Awareness of pharmacists and consumers towards protective effects of sunscreens against skin cancer
-
Efficacy of Oral Vitamin D3 Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium) January 2021Journal of Nutritional Science and Vitaminology 67(1):68-71 DOI: 10.3177/jnsv.67.68
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Clopidogrel-Vonoprazan Fumarate Interaction May Lead to Gastric Complications: an In Silico Prediction 40(1):126-156
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The Impact of Oral Ciprofloxacin on the Structure and Functions of Rat Gastric Mucosa.
Nihal Abdalla Ibrahim*, The Impact Of Apelin Ligand Binding On APJ Receptor on the Various Physiological And Pathophysiological Aspects Of Metabolism and Homeostasis. Europ J. of Pharm. And Med. Res., 2017,4 (01), 61-69. ISSN 2394-3211 EJPMR Impact Factor 3.628
Ahmed Gaili, Sundos Qasim, Zakia Metwali , Nihal Abdalla and Sara Al –Akshar The Relationship Between Knowledge and Drug Adherence in Hypertensive Patients: A Cross Sectional Study in UAE. A J A D D [4][01][2016]001-011 American Journal of Advanced Drug Delivery, www.ojadd.com, ISSN 2321-547X.
Ibrahim Nihal A*, A Effect of High Fat Diet and High Protein Diet on Fasting Serum Ghrelin Level in Type-1 Diabetes International Research Journal of Medical Sciences. ISSN 2320 –7353 Vol. 3(6), 5-14, June (2015) Int. Res. J. Medical Sci. International Science Congress Association
Farajallah A , Abdalla N, Ahmed A , Abusnena S. The Relationship between Type 2 Diabetes and Total Ghrelin Level in a Population Sample in the United Arab Emirates. IOSR Journal Of Pharmacy (e)-ISSN: 2250-3013, (p)-ISSN: 2319-4219 www.iosrphr.org Volume 4, Issue 6 (June 2014), PP. 01-08 1
Metwalli Z, Abdalla N* , El Barrani R. A Natural Alternative to Conventional Antibiotics. Res J Ph B Ch Sc. 2014 RJPBCS, ISSN: 0975-8585 July - August 2014, 5(4) , PP. 588-599
El Serougy M, Nihal A, Salma N, Madi M. Effect of crude toxin extracted from the Red Sea fish Lagocephalus Scleratus on salivary secretion in dogs. Bulletin of Egyptian Society of Physiological Sciences, 1992 March, 12(2), P. 101
Nihal A, El Serougy M, Salma N, Madi M. Effect of crude toxin extracted from the Red Sea fish Lagocephalus Scleratus on some aspects of carbohydrates and lipids metabolism in anesthetized dogs. Bulletin of Egyptian Society of Physiological Sciences, 1992 March, 12(2), P. 65.
Ebtesam Khalil, Nihal A. Ibrahim, Maher Al Shayeb, Syed Kuduruthullah, Mawada Hassan, Stress-related Oral manifestations disorders in a population sample of patients attending Ajman University dental clinics.Journal of International Dental and Medical Research,2020, 13(1)
Ibrahim NA*, Nabil N, Ghaleb S. Pathophysiology of the risk factors associated with osteoporosis and their correlation to the T-score value in patients with osteopenia and osteoporosis in the United Arab Emirates. J Pharm Bioall Sci 2019;11:364-72
Ibrahim NA*, Edis Z, Al Owais KS, Adherence of Geriatric patients and their beliefs Towards their medicines in the United Arab Emirates. J Pharm Bioall Sci. ,2020;12:22-300
Nihal Abdalla Ibrahim *, Zehra Edis, Klaithem Salem Al-Owais, ROLE OF PHYSICIANS IN DRUG ADHERENCE OF GERIATRIC PATIENTS IN THE UNITED ARAB EMIRATES. Int. Res. J. Pharm. 2018, 9 (9)
Nihal Abdalla Ibrahim, Nada Mohamed Saleh, Fatima Koprulu* , Altaf Hani Abdulrahim ;Metabolic syndrome associated risk factors: Findings among female university students in the United Arab Emirates. J pharmacy and Pharmaceutical Sciences. Accepted. in press
Nurses’ Perception regarding Pharmaceutical Care Practice: a Qualitative Approach, Tropical Journal of Pharmaceutical Research, Accepted
Exploring Community Pharmacists’ Perception towards Responsible Provision of Patient Care Services : A Quantitative Assessment. Tropical Journal of Pharmaceutical Research. Accepted
Stress‑Related Oral Manifestations Disorders in A Population Sample of Patients Attending Ajman University Dental Clinics
Psychological stress adversely affects the physiological functions of the body to a significant point leading to various psychosomatic diseases. These diseases have physical symptoms originating from mental or emotional causes, most common of which are stress, anxiety, and depression. The oral mucosa is highly sensitive and reactive to stress. Common oral problems related to stress are MPDS, aphthous ulcers, oral lichen planus, xerostomia, burning mouth syndrome, and bruxism. In the present study, we aimed to study the stress-related oral manifestations and relate it to the type of stress and other psychosomatic disorders in patients attending Ajman University dental clinics. Results showed 46% of the participants in the study had combined two or more stress- related oral manifestations mainly attrition, bruxism, xerostomia, recurrent aphthous ulcer and chronic periodontal diseases, followed by 10.7% diagnosed with generalized attrition and 10% reported with the localized type. The least oral manifestation associated with erosion and MPDS (0.7%). Concluding that, stress and other psychogenic factors play an essential role as contributory factors in the development and progression of oral lesions.
About the journal
Thyroid cancer risk factors and Pakistani University students’ awareness towards its preventive practice
Objectives: Thyroid Cancer is one of the rarest cancers but its prevalence has been increasing worldwide for the last couple of decades. Methods: The data collection tool was designed to assess knowledge, awareness, perception, and attitude towards preventive practices of thyroid cancer in Pakistani university students. The data were collected over a duration of six months and a total number of 3722 students participated. Results: The knowledge of risk factors of thyroid cancer was an important parameter of this study. The students who knew all the early signs of thyroid cancer were 28.7%. In this study, the independent variables such as age, gender, demographic location, and financial status were found to be highly significant with knowledge, attitude towards warning signs of cancer, and the perception of students about developing thyroid cancer. Conclusions: The participants were found to have poor knowledge about early signs of thyroid cancer. The study participants perception, behavior, and attitude towards preventive practices of thyroid cancer were found inadequate and appropriate measures on a National level should be taken to enhance the knowledge about preventive practices of thyroid cancer. Increasing knowledge and awareness shall help decrease the overall morbidity and mortality linked with thyroid carcinomas and thyroid diseases.
About the journal
Recent strategies driving oral biologic administration
ABSTRACT Introduction: High patient compliance, noninvasiveness, and self-administration are the leading features of vaccine delivery through the oral route. The implementation of swift mass vaccination campaigns in pandemic outbreaks fascinates the use of oral vaccination. This approach can elicit both mucosal and systemic immune responses to protect against infection at the surface of the mucosa. Area covered: As pathogen entry and spread mainly occurs through the gastrointestinal tract (GIT) mucosal surfaces, oral vaccination may protect and limit disease spread. Oral vaccines target various potential mucosal inductive sites in the GIT, such as the oral cavity, gastric area, and small intestine. Orally delivered vaccines having subunit and nucleic acid pass through various GIT-associated risks, such as the biodegradation of biologics and their reduced absorption. This article presents a summarized review of the existing technologies and prospects for oral vaccination. Expert opinion: The intestinal mucosa focuses on current approaches, while future strategies target new mucosal sites, i.e. oral cavity and stomach. Recent developments in biologic delivery through the oral route and their potential use in future oral vaccination are mainly considered.
About the journal
Potential of Nanocarrier-Based Drug Delivery Systems for Brain Targeting: A Current Review of Literature
The advent of nanotechnologies such as nanocarriers and nanotherapeutics has changed the treatment strategy and developed a more efficacious novel drug delivery system. Various drug delivery systems are focused on drug-targeting of brain cells. However, the manifestation of the brain barrier is the main hurdle for the effective delivery of chemotherapeutics, ultimately causing treatment failure of various drugs. To solve this problem, various nanocarrier-based drug delivery system has been developed for brain targeting. This review outlines nanocarrier-based composites for different brain diseases and highlights nanocarriers for drug targeting towards brain cells. It also summarizes the latest developments in nanocarrier-based delivery systems containing liposomal systems, dendrimers, polymeric micelles, polymeric nanocarriers, quantum dots (QDs), and gold nanoparticles. Besides, the optimal properties of nanocarriers and therapeutic implications for brain targeting have been extensively studied. Finally, the potential applications and research opportunities for nanocarriers in brain targeting are discussed. Keywords: brain targeting, nanocarriers, blood–brain barrier, nanotherapeutics, in-vivo
About the journal
Mechanistic Investigations of Ellagic Acid via Topological and Functional Analysis of its Protein Interaction Network LATIN AMERICAN JOURNAL OF PHARMACY 40 (6), 1273-1280
Ellagic acid is a phenolic compound which is the potent inhibitor of carcinogenesis. However, the exact mode of action is still not known. The main purpose of this study was to investigate the action mechanism of ellagic acid based on network pharmacology, protein-protein interaction database and evaluation of biological processes through Cytoscape plugin ClueGO. The protein targets of ellagic acid were retrieved through TCMSP and STITCH database. The interaction between the retrieved targets of ellagic acid was investigated by STITCH, GO enrichment and pathway enrichment analysis. The study revealed that there are total of 20 protein targets as a result of target search. In addition, 42 GO terms were also retrieved, which were found to be related with biological process. 10 GO terms related to several molecular processes and 2 GO terms achieved by analyzing gene function were annotated based on Kyoto Encyclopedia of Gene and Genomic pathways. Most of the terms were found to be associated with anticancer and antioxidant pathways such as NME1-NME2, and CA2 are involved in treating cancer metastasis and suppressing carcinogenesis respectively. Ellagic acid has potential of treating cancer, pigmentation, oxidative stress and viral infection with an underlying mechanism of cancer suppression. This study can be used for better understanding of mode of action of ellagic acid. Still further research studies such as docking and MD stimulation are required to elaborate the pharmacological and toxicological effects of ellagic acid.
About the journal
In Silico Prediction of the Mechanism of Radix Paeoniae Rubra against Menstruation Disorder
About the journal
An exploration of knowledge, attitude, and practices of physicians towards pharmacovigilance at tertiary care hospitals in Khyber-Pakhtunkhwa province, Pakistan
Drug safety assures the effectiveness, safety, and security of drugs, vaccines, and other biologicals to protect public health. Medication-related errors coupled with unjudicial medication practices often cause a catastrophic impact on the healthcare system globally. The present study aimed to assess the knowledge, attitude, and practice of physicians toward pharmacovigilance and barriers to adverse drug reaction (ADR) reporting at tertiary care hospitals in Khyber-Pakhtunkhwa (KP) province, Pakistan. A descriptive cross-sectional study was conducted among registered doctors working in seven tertiary care hospitals from seven administrative divisions of KP province of Pakistan from July 2019 to March 2020. During the study period, 358 physicians who fulfilled the inclusion criteria and agreed to participate completed and returned the validated structured questionnaires. Descriptive and inferential statistics were applied for data analysis. The majority of physicians had poor knowledge (81.3%) regarding pharmacovigilance along with poor reporting practices (94.9%), although (96.5%) had a positive attitude toward ADR reporting. A significant barrier identified was the unavailability of reporting forms (95.9%), whereas mandatory ADR reporting (96.2%) was the major factor to encourage ADR reporting. Physicians aged ≥ 41 and experience ≥ 11 years had significantly more knowledge than other categories (P < 0.001). Significant association (P < 0.001) of physicians' knowledge and practice were found where 77.2% of the participants having poor knowledge reported poor practices. Physicians' understanding of pharmacovigilance was suboptimal, although they have a positive attitude toward ADR reporting. Thus, there is a need for continuous education and training programs to support pharmacovigilance activities that could improve physicians' understanding.
About the journal
Awareness of pharmacists and consumers towards protective effects of sunscreens against skin cancer
The objective of the present study was to assess the awareness level of individuals on the use of sunscreen products, and pharmacists’ perception of sunscreen safety. A cross-sectional, descriptive study was conducted in the United Arab Emirates (UAE). Participants involved included 224 female undergraduates of Ajman University (aged 18-25 years old), 234 patients visiting numerous pharmacies, and 58 pharmacists from the private sector in Dubai. Questionnaires were designed and distributed to all participants. Data entry and analysis were performed using SPSS (Statistical Program for Social Sciences) version 20. Among female undergraduate students, 94.7% used sun protection, 81.1% understood what is meant by SPF (Sun Protection Factor) Value, and 70.2% used the optimal SPF (15-20). Additionally, 95.2% reported that sunscreens do not have any side effects. Out of the 234 patients who participated in the study, 86.8% used sun protection, 56.8% understood what is meant by SPF, and 43.2% used the optimal SPF. Furthermore, 93.2% stated that sunscreens do not have any side effects. Female patients were found to use sunscreens with higher SPF values (above 50) as compared to male patients (P 0.024). Patients above the age of 40 also used sunscreens with high SPF (P 0.001). As for pharmacists, they all agreed that sunscreens have a marked safety profile, with no side effects, and that the optimal SPF for use is 15-20. Most pharmacists (80%) reported that consumers are in fact aware and knowledgeable about the proper use and application of sunscreens. Optimal use of routine sunscreen is of paramount importance to prevent skin damage as well as cancer.
About the journal
Efficacy of Oral Vitamin D3 Therapy in Patients Suffering from Diffuse Hair Loss (Telogen Effluvium) January 2021Journal of Nutritional Science and Vitaminology 67(1):68-71 DOI: 10.3177/jnsv.67.68
The aim of the present study was to estimate the prevalence of telogen effluvium (TE) and to evaluate the efficacy of vitamin D in the treatment of this problem in women belonging to various cities of south Punjab, Pakistan. In the present study, 40 adult women suffering from the problem of TE were included. Each woman was treated with oral vitamin D3 (200,000 IU) therapy fortnightly and a total of 6 doses were given to each patient. After 15 d of the last dose, the condition of patients was assessed clinically. The mean age of female patients was 32.2±1.5 y, 42.5% of the patients between 21-30 y of age were found to be more frequently affected with TE compared to 35% females of 31-40 y of age. Results showed significant improvement in hair growth in young (r=0.457 p
About the journal
Clopidogrel-Vonoprazan Fumarate Interaction May Lead to Gastric Complications: an In Silico Prediction 40(1):126-156
The purpose was to identify the potential effects for clopidogrel-vonoprazan fumarate interaction. ChemDIS-Mixture was applied for the theoretical assessment of potential outcomes for coexposure of two drugs, vonoprazan fumarate and clopidogrel. This study was executed at low confidence score (0.15). The level of significance for the adjusted p-value is set at 0.05 along with Benjamini-Hochberg multiple test correction. Resultantly, the overlapped disease ontology (DO) terms of stomach disease (DOID: 76), gastritis (DOID: 4029), and peptic ulcer disease (DOID: 750) were identified for vonoprazan fumarate and clopidogrel. The incidence of stomach disease and gastritis were significantly higher (p < 0.05) than the clopidogrel alone. According to these findings, clopidogrel-vonoprazan fumarate interaction may lead to gastric complications.
About the journal
The Impact of Oral Ciprofloxacin on the Structure and Functions of Rat Gastric Mucosa.
Ciprofloxacin (CPX), is a fluoroquinolone antibiotic used to treat a number of gram-negative and gram-positive bacterial infections. Ciprofloxacin can cause severe side effects, ranging from tendon problems, nerve damage, to serious mood or behavior changes. The purpose of this study was to investigate how ciprofloxacin affects gastric cell lines in rats with a distinctive emphasis on physiological, histopathological, and bacteriological changes. Male albino rats (n =21) were distributed into three groups; control, CPX, and CPX-withdrawal groups. The treated rats were given CPX tablets (12.5 mg/kg) dissolved in carboxymethyl cellulose (CMC) 0.5 % orally once daily via gavage for sixty consecutive days. Control rats received only the vehicle. The withdrawal group was treated for 60 days and the drug was withdrawn for another sixty days. After completion of the experiment, all rats were sacrificed and gastric tissues were treated for light, immunohistochemical, and scanning electron microscopic examination. Image J software was used to measure immune-labeled gastric epithelial cells. Blood samples were also collected for H. Pylori immunoglobulins IgM, IgA, and IgG. Results showed that treated rats acquired significantly strongly positive tumor necrosis factor (TNFα) and significant reduction of serum level of H. pylori IgM, IgA, and IgG in all the study groups. It could be concluded that prolonged oral CPX administration to albino rats changes the gastric mucosal architecture and bacteriology.
About the journal
Conference Presentation
- Abdalla, N., and Jamal, M. “Hemophilia: Is It a Real Threat in the UAE?” Dubai International Pharmaceuticals and Technology Conference and Exhibition, DUPHAT. 7-9 March 2017. Poster Presentation.
- Koujan, Gh., Ibrahim, N., and Ali, A. "Knowledge, Attitude, and Practice (KAP) Toward Menstruation Among Medical and Non-Medical Female Students at Ajman University of Science and Technology." Dubai International Pharmaceuticals and Technology Conference and Exhibition, DUPHAT. March 2016.
- Ahmed, A., Abdalla, N., Ali, A., and Abu Senina, S. "The Relationship Between Total Ghrelin and Type 2 Diabetes in a Population Sample in the UAE." Dubai International Pharmaceuticals and Technology Conference, DUPHAT. March 2014.
- Metwali, Z., Abdalla, N., and El Barrani, R. "A Natural Alternative to Conventional Antibiotics." Dubai International Pharmaceuticals and Technology Conference, DUPHAT. March 2013.
- Abdalla, N., and Magdy, A. "Ghrelin and Leptin: Are They the Future of Obesity Treatment?" Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 12-14 March 2012, Dubai, UAE.
- Abdalla, N., Munzir, M., and Al Hamed, N. "Osteoarthritis: A Recent Approach." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 12-14 March 2012, Dubai, UAE.
- Abdalla, N., Cekir, N., Anwar, F., and Khan, A. "Food and Diseases: You Are What You Eat." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 12-14 March 2012, Dubai, UAE.
- Abdalla, N., Hassan, N., and Mukhtar, M. "Ghrelin: Is It the Future Treatment of Diabetes?" Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 22-24 March 2011, Dubai, UAE.
- Abdalla, N., Habbobi, S., Nabil, N. "Osteoporosis: The Silent Thief." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 15-17 March 2010, Dubai, UAE.
- Abdalla, N. "Ghrelin, Appetite, and Weight Control." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, March 2010, Dubai, UAE.
- Abdalla, N., Mohamed, Kh. "Breast Cancer in the UAE," Dubai International Pharmaceuticals and Technology, 10-12 March 2008, Dubai, UAE.
- Seminar: "The Role of Bile Acids and Their Receptors in Metabolic Regulation," Faculty of Medicine, Alexandria University. Proceedings of the Physiology Department, April 2010.
- Seminar: "Apelin: A Friend, Not a Foe," Faculty of Medicine, Alexandria University. Proceedings of the Physiology Department, March 2010.
- Seminar: "Vitamin D Deficiency and Osteoporosis," Al Mushieref Medical Center, Ajman Medical District, Ministry of Health, UAE, 16. 2. 2012.
- Seminar: "First Aid, CPR, and Basic Life Support," Al Mushieref Medical Center, Ajman Medical District, Ministry of Health, UAE, 12.4.2012
- K. El Morshedi, M. Buabeid, N. Ibrahim, "Histological Changes in the Endometrium of Female Albino Rat Uterus Under the Effect of Clomiphene Citrate," Abu Dhabi Pharmaceutical Conference, 2019.
Abdalla, N., and Jamal, M. “Hemophilia: Is It a Real Threat in the UAE?” Dubai International Pharmaceuticals and Technology Conference and Exhibition, DUPHAT. 7-9 March 2017. Poster Presentation.
Koujan, Gh., Ibrahim, N., and Ali, A. "Knowledge, Attitude, and Practice (KAP) Toward Menstruation Among Medical and Non-Medical Female Students at Ajman University of Science and Technology." Dubai International Pharmaceuticals and Technology Conference and Exhibition, DUPHAT. March 2016.
Ahmed, A., Abdalla, N., Ali, A., and Abu Senina, S. "The Relationship Between Total Ghrelin and Type 2 Diabetes in a Population Sample in the UAE." Dubai International Pharmaceuticals and Technology Conference, DUPHAT. March 2014.
Metwali, Z., Abdalla, N., and El Barrani, R. "A Natural Alternative to Conventional Antibiotics." Dubai International Pharmaceuticals and Technology Conference, DUPHAT. March 2013.
Abdalla, N., and Magdy, A. "Ghrelin and Leptin: Are They the Future of Obesity Treatment?" Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 12-14 March 2012, Dubai, UAE.
Abdalla, N., Munzir, M., and Al Hamed, N. "Osteoarthritis: A Recent Approach." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 12-14 March 2012, Dubai, UAE.
Abdalla, N., Cekir, N., Anwar, F., and Khan, A. "Food and Diseases: You Are What You Eat." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 12-14 March 2012, Dubai, UAE.
Abdalla, N., Hassan, N., and Mukhtar, M. "Ghrelin: Is It the Future Treatment of Diabetes?" Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 22-24 March 2011, Dubai, UAE.
Abdalla, N., Habbobi, S., Nabil, N. "Osteoporosis: The Silent Thief." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, 15-17 March 2010, Dubai, UAE.
Abdalla, N. "Ghrelin, Appetite, and Weight Control." Dubai International Pharmaceuticals & Technologies Conference and Exhibition, DUPHAT, March 2010, Dubai, UAE.
Abdalla, N., Mohamed, Kh. "Breast Cancer in the UAE," Dubai International Pharmaceuticals and Technology, 10-12 March 2008, Dubai, UAE.
Seminar: "The Role of Bile Acids and Their Receptors in Metabolic Regulation," Faculty of Medicine, Alexandria University. Proceedings of the Physiology Department, April 2010.
Seminar: "Apelin: A Friend, Not a Foe," Faculty of Medicine, Alexandria University. Proceedings of the Physiology Department, March 2010.
Seminar: "Vitamin D Deficiency and Osteoporosis," Al Mushieref Medical Center, Ajman Medical District, Ministry of Health, UAE, 16. 2. 2012.
Seminar: "First Aid, CPR, and Basic Life Support," Al Mushieref Medical Center, Ajman Medical District, Ministry of Health, UAE, 12.4.2012
K. El Morshedi, M. Buabeid, N. Ibrahim, "Histological Changes in the Endometrium of Female Albino Rat Uterus Under the Effect of Clomiphene Citrate," Abu Dhabi Pharmaceutical Conference, 2019.
Memberships, Awards and Honors
- Member of the Egyptian Medical Syndicate.
- Member of the Physiology Society of Medical Colleges.
- Award for Supervising the Best Research Paper, The 9th Student Scientific Conference, Faculty of Pharmacy, AUST, May 2013.
- Award for Supervising the Best Scientific Students' Poster and Presentation, DUPHAT, March 2013.
- Award for Supervising the Best Research Paper, The 8th Students' Scientific Conference, Faculty of Pharmacy, AUST, 16 May 2012.
- Award for Active Contribution in the Medical Program "Prevention before Treatment," Ministry of Health, Ajman Medical District, May 2012.
- Award for Supervising the 2nd Best Scientific Students' Poster, DUPHAT, March 2011.
- Award for Supervising the 3rd Best Scientific Students' Poster and Presentation, DUPHAT, March 2010.
- Award for Supervising the Best Scientific Graduation Project, The 5th Students' Scientific Conference, Faculty of Pharmacy, AU, May 2009.
- Award for Supervising the Best Scientific Graduation Project, The 4h Students Scientific Conference, Faculty of Pharmacy, AUST, May 2008.
- Certificate of Appreciation for Active Contribution to the Gulf Education & Training Exhibition (GETEX 2011), Dubai, April 2011.
- Certificate of Appreciation for Active Contribution as Assessor during the 7th Approach Student Scientific Conference, AUST, May 8-9, 2011.
- Certificate of Appreciation for Active Contribution during the Anti-Smoking Workshop, AUST, 8.12.2010
- Award for Supervising the Eighth Best Innovative Poster, DUPHAT 2018.