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Yehia Saleh Ahmed Mohamed
- Associate Professor
- Ext: 5337
Dr. Yehia is an associate professor of immunology and infectious diseases. He gained his undergraduate degree from Al-Azhar University in Cairo, Egypt, and his PhD from the Department of Infection, Immunity, and Inflammation at Leicester University Medical School, UK (ranked 285th globally and 34th in the UK according to the QS report 2025). Dr. Yehia received his training as a PDF at the Jenner Institute-Oxford University, where he served as an immunology scientist to monitor the cellular responses to two HIV-vaccine clinical trials. As an academic, Dr. Yehia’s teaching journey spans many global destinations, including the Middle East, Europe, and North America, during which he focused on subject-oriented curriculum development, course coordination, student mentoring, and community service. Dr. Yehia is interested in many areas of immunology and infectious diseases. These include developing vaccines for chronic respiratory and retroviruses, immunotherapy of tumors, exploring the immune-modulating effects of new medicines, and discovering and studying new natural bio-remedies with antimicrobial and antitumor potential.
Education
- Postgraduate Diploma, Medical Lab Technologies, Anderson College, ON, Canada. 2020
- Postdoctoral Fellowship; molecular HIV-1 vaccine development, Jenner Institute, Oxford University, UK. 2018
- PhD; Infection, Immunity, and Inflammation, School of Medicine, Leicester University, UK, 2012
- B. Pharm; Al-Azhar University, Cairo, Egypt.
Postgraduate Diploma, Medical Lab Technologies, Anderson College, ON, Canada. 2020
Postdoctoral Fellowship; molecular HIV-1 vaccine development, Jenner Institute, Oxford University, UK. 2018
PhD; Infection, Immunity, and Inflammation, School of Medicine, Leicester University, UK, 2012
B. Pharm; Al-Azhar University, Cairo, Egypt.
Experience
- College of Medicine, Ajman University, Associate Professor, Sep 2020 - present
- Medical Lab Specialist, MOHAP, Egypt. 2020- present
- Western University, London-Ontario, Visiting Research Scholar, 2019- 2020
- Jenner Institute, Oxford University, UK, Immunology Research Scientist, 2017- 2019
- Department of Medical Microbiology and Immunology, College of Medicine, IAU, Saudi Arabia, Assistant Professor, 2012 – 2019
- PhD Candidate, Research Assistant, Department of Infection, Immunity, and Inflammation, Leicester University, UK. 2007- 2012
- Teaching Assistant, Microbiology and Immunology Dept., Al-Azhar University, Cairo, Egypt. 2003- 2007
College of Medicine, Ajman University, Associate Professor, Sep 2020 - present
Medical Lab Specialist, MOHAP, Egypt. 2020- present
Western University, London-Ontario, Visiting Research Scholar, 2019- 2020
Jenner Institute, Oxford University, UK, Immunology Research Scientist, 2017- 2019
Department of Medical Microbiology and Immunology, College of Medicine, IAU, Saudi Arabia, Assistant Professor, 2012 – 2019
PhD Candidate, Research Assistant, Department of Infection, Immunity, and Inflammation, Leicester University, UK. 2007- 2012
Teaching Assistant, Microbiology and Immunology Dept., Al-Azhar University, Cairo, Egypt. 2003- 2007
Teaching Area
- Basic Medical Immunology
- Clinical and Diagnostic Immunology
- Microbiology and Infectious Diseases
Basic Medical Immunology
Clinical and Diagnostic Immunology
Microbiology and Infectious Diseases
Research
- Cellular and adoptive immunotherapy of malignant tumors
- Immunologic evaluation of molecular vaccine candidates for chronic viral infections
- The immunomodulatory profiling of newly approved therapeutic agents
- Clinical trials and survey studies related to communicable and non-communicable chronic diseases.
- Exploring and evaluation of natural metabolites with anti-microbial and anti-proliferative potentials
Cellular and adoptive immunotherapy of malignant tumors
Immunologic evaluation of molecular vaccine candidates for chronic viral infections
The immunomodulatory profiling of newly approved therapeutic agents
Clinical trials and survey studies related to communicable and non-communicable chronic diseases.
Exploring and evaluation of natural metabolites with anti-microbial and anti-proliferative potentials
Publications
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Book ChapterMourad Aribi, Yehia Mohamed, Jaeyoung Kim and Nikita Thapa, et al., The Future of HIV Vaccine Development, Learned Lessons from COVID-19 Pandemic. Pharmaceutical Science. IntechOpen; 2024. Available from: http://dx.doi.org/10.5772/intechopen.111005, New Topics in Vaccine Development, IntechOpen, ISBN: 978-1-83768-629-2
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JournalSinclair Steele, Gabriel Andrade, Marwah Abdulkader and Yehia Mohamed. , Sinclair Steele, Gabriel Andrade, Marwah Abdulkader and Yehia Mohamed. Medical school origins of award-winning pathologists; analysis of a complete national dataset. BMC Medical Education (2024) 24:814, BMC Medical Education, Aug 2024
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JournalYehia S. Mohamed , Mamoun Mukhtar, Akrem Elmalti, Khalid Kheirallah, Debadatta Panigrahi, Eman Y. Abu-rish, Ibrahim Bani, Eiman Mohamed Nasor, Wafa Ahmed and Abdallah Alzoubi, Yehia S. Mohamed, Mamoun Mukhtar, Akrem Elmalti, Khalid Kheirallah, Debadatta Panigrahi, Eman Y. Abu-rish, Ibrahim Bani, Eiman Mohamed Nasor, Wafa Ahmed and Abdallah Alzoubi. Hospital Mortality and Morbidity in Diabetic Patients with COVID-19: A Retrospective Analysis from the UAE. Int. J. Environ. Res. Public Health 2024, 21, 697. https://doi.org/10.3390/ ijerph21060697, International journal of environmental research and public health, Vol: 21, pp.697 - 708, May 2024
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JournalIbrahim Bani, Yehia Mohamed, Gabriel Andrade. Evaluation of the impact of COVID-19 on stress and burnout among Ajman university (AU) medical students. Acta Psychologica 246 (2024) 104245, Acta Psychologica, Vol: 246, Apr 2024
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JournalYehia S. Mohamed, Anastasiya Spaska , Gabriel Andrade , Mohamed A. Baraka, Hafiz Ahmad, Sinclair Steele, Eman Y. Abu-rish, Eiman Mohamed Nasor, Kowthar Forsat , Hajar Jamal Teir , Ibrahim Bani , Debadatta Panigrahi. Hand hygiene knowledge, attitude, and practice before, during and post COVID-19: a cross-sectional study among university students in the United Arab Emirates. Infection Prevention in Practice 6 (2024) 100361, Infection Prevention in Practice, Vol: 6, Mar 2024
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JournalMamoun Mukhtar, Yehia S. Mohamed, Murtada Elbagir, Yohannes Tesfa, Sami Kenz, Vijay Kumar, Sijomol Skaria, Mohamed A. Baraka, Ghassan Darwich, Akrem Elmalti. Vitamin B12 Status Among Patients With Type 2 Diabetes Mellitus. J Endocrinol Metab. 2024;14(1):33-39, J Endocrinol Metab, Vol: 14, Feb 2024, doi: 10.14740
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JournalPanigrahi, D., Mohamed, Y.S., Khan, E., Panigrahi, D., Mohamed, Y.S., Khan, E. (2023). Enhancing Lecture Attendance: A Novel Approach Utilizing Clinical Case-Based Learning. Adv Mach Lear Art Inte, 4(2), 41-43., Advances in Machine Learning & Artificial Intelligence(AMLAI), Vol: 4, pp.41 - 43, Oct 2023
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JournalDebadatta Panigrahi, Erum Khan, Yehia Mohamed and Ashok Rattan. , Debadatta Panigrahi, Erum Khan, Yehia Mohamed and Ashok Rattan. Factors Affecting Patients Test Results". Acta Scientific Microbiology 5.10 (2022): 59-67., Act Scientific Microbiology, Vol: 5, pp.59 - 67, Sep 2022
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Mohamed A. Baraka, Amany Alboghdadly, Samar Alshawwa, Asim Ahmed Elnour, Hassan Alsultan, Taha Al, Hussain Alaithan, Md. Ashraful Islam, Kareem Ahmed El-Fass, Yehia Mohamed, Abdulsalam A. Alasseri and Khairi Mustafa Fahelelbum. Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences: A Cross Sectional Study in Eastern Province of Saudi Arabia. Antibiotics 2021, 10, 878. https://doi.org/10.3390/antibiotics10070878
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Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Zara Hannoun, Alison Crook, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, and Tomáš Hanke. Specificity of CD8 T-Cell Responses following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya. Vaccines 2020, 8(2), 260 https://www.mdpi.com/2076-393X/8/2/260 2
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Yehia S. Mohamed, Borthwick N, Hanoon Z. Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines. BSI congress. Dec 2019. https://www.eventsforce.net/bsi/frontend/reg/absViewDocumentFE.csp?documentID=265
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Wafaa S.S. Khalaf, Mamta Garg, Yehia S. Mohamed, Cordula Stover, Michael J Browning. In vitro generation of cytotoxic T cells with the potential for adoptive tumour immunotherapy of Multiple Myeloma. Frontiers Immunology. Aug. 2019; (10): 1792. https://doi.org/10.3389/fimmu.2019.01792
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Eman Y. Abu-Rish, Lina A. Dahabiyeh, Yasser Bustanjia, Yehia S. Mohamed, Michael J. Browning. Effect of lamotrigine on in vivo and in vitro cytokine secretion in murine models of inflammation. Neuroimmunology. Sep. 2018; (322): 36-45. https://doi.org/10.1016/j.jneuroim.2018.06.008
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Eman Y. Abu-Rish, Shada Y. Elhayek, Yehia S. Mohamed, Islam Hamad and Yasser Bustanji. Evaluation of immunomodulatory effects of lamotrigine in Balb/c mice. Acta Pharm. Sept. 2017; 67(4) https://doi.org/10.1515/acph-2017-0035
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Yehia S. Mohamed, Wafaa Khalaaf and Michael Browning. APC / tumour cell hybrid vaccines in cancer immunotherapy. Immunotherapy - Myths, Reality, Ideas and Future. InTech Open access publishing, April 2017. Edited by Krassimir Metodiev, ISBN 978-953-51-3106-9. https://www.intechopen.com/books/immunotherapy-myths-reality-ideas-future
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Yehia S. Mohamed, Layla A. Bashawri, Chittibabu Vatte, Cyril Cyrus, Eman Y. Abu-rish, Wafaa S. Khalaaf and Michael J. Browning. The in vitro generation of multi-tumor antigen-specific cytotoxic T cell clones: Candidates for leukemia adoptive immunotherapy following allogeneic stem cell transplantation. Molecular Immunology. Sept. 2016; (77):79–88. https://doi.org/10.1016/j.molimm.2016.07.012
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Eman Y. Abu-Rish, Mohammad K. Mohammad, Mohammad M. Hudaib, Sundus Mashalla, Loay Mashallah, Violet Kasabri, Khaled Tawaha, Yehia S. Mohamed, Yasser K. Bustanji. Evaluation of the antiproliferative activity of some traditional anticancer herbal remedies from Jordan. Trop J Pharm Res, March 2016; 15(3): 469. http://dx.doi.org/10.4314/tjpr.v15i3.6
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Yehia S. Mohamed and Michael Browning. Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro. Cancer Immunol Res Jan 2016; (4): B099. https://cancerimmunolres.aacrjournals.org/content/4/1_Supplement/B099
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Al-Amri, Ali M., Vatte, Chittibabub; Cyrus, Cyril, Chathoth, Shahanas, Hashim, Tariq Mohammad, Yehia S. Mohamed, Ali, Rudaynah Ala, Alsaid, Abira, Ali, Amin Al. Novel mutations of the PIK3CA gene in head and neck squamous cell carcinoma. Cancer Biomarkers. Jan. 2016; 16(3) :377-383. http://DOI: 10.3233/CBM-160576
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Yehia S. Mohamed. Tumor-specific cytotoxic T lymphocytes: A candidate for adoptive immunotherapy of hematological malignancies. Clin Pharmacol Biopharm. Nov 2015; 4(4); 124. DOI: 10.4172/2167-065X.C1.014 12
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Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, Sarah Alderson and Michael J. Browning. In vitro evaluation of human hybrid cell lines generated by fusion of Blymphoblastoid cells and ex vivo tumour cells as candidate vaccines for haematological malignancies. Vaccine. Oct 2012; 30(46):6578-87. https://doi.org/10.1016/j.vaccine.2012.08.032 13.
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Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, and Michael J. Browning. Long-lived fusions of human haematological tumour cells and B-lymphoblastoid cells induce tumour antigen-specific cytotoxic T-cell responses in vitro. Immunobiology. July 2012; 217(7):719-29. https://www.sciencedirect.com/science/article/pii/S0171298511002610
Mourad Aribi, Yehia Mohamed, Jaeyoung Kim and Nikita Thapa, et al., The Future of HIV Vaccine Development, Learned Lessons from COVID-19 Pandemic. Pharmaceutical Science. IntechOpen; 2024. Available from: http://dx.doi.org/10.5772/intechopen.111005, New Topics in Vaccine Development, IntechOpen, ISBN: 978-1-83768-629-2
New Topics in Vaccine Development explores the latest advancements and future directions in vaccine technology across 11 chapters, each addressing a different and specific facet. This book is an essential resource for clinicians, researchers, scientists, and students in immunology aiming to deepen their understanding of this crucial field.
About the journal
Sinclair Steele, Gabriel Andrade, Marwah Abdulkader and Yehia Mohamed. , Sinclair Steele, Gabriel Andrade, Marwah Abdulkader and Yehia Mohamed. Medical school origins of award-winning pathologists; analysis of a complete national dataset. BMC Medical Education (2024) 24:814, BMC Medical Education, Aug 2024
Background: The ultimate aim of medical education is to produce successful practitioners, which is a goal that educators, students and stakeholders support. These groups consider success to comprise optimum patient care with consequently positive career progression. Accordingly, identification of the common educational features of such high-achieving doctors will facilitate the generation of clinical excellence amongst future medical trainees. In our study we source data from British clinical merit award schemes and subsequently identify the medical school origins of pathologists who have achieved at least national distinction. Methods: Britain operates Distinction Award/Clinical Excellence Award schemes which honour National Health Service doctors in Scotland, Wales and England who are identified as high achievers. This quantitative observational study used these awards as an outcome measure in an analysis of the 2019-20 dataset of all 901 national awardwinning doctors. Where appropriate, Pearson’s Chi-Square test was applied. Results: The top five medical schools (London university medical schools, Aberdeen, Edinburgh, Oxford and Cambridge) were responsible for 60.4% of the pathologist award-winners, despite the dataset representing 85 medical schools. 96.4% of the pathologist merit award-winners were from European medical schools. 9.0% of the pathologist award-winners were international medical graduates in comparison with 11.4% of all 901 award-winners being international medical graduates. Conclusions: The majority of pathologists who were national merit award-winners originated from only five, apparently overrepresented, UK university medical schools. In contrast, there was a greater diversity in medical school origin among the lower grade national award-winners; the largest number of international medical graduates were in these tier 3 awards (13.9%). As well as ranking educationally successful university medical schools, this study assists UK and international students, by providing a roadmap for rational decision making when selecting pathologist and non-pathologist medical education pathways that are more likely to fulfil their career ambitions.
About the journal
Yehia S. Mohamed , Mamoun Mukhtar, Akrem Elmalti, Khalid Kheirallah, Debadatta Panigrahi, Eman Y. Abu-rish, Ibrahim Bani, Eiman Mohamed Nasor, Wafa Ahmed and Abdallah Alzoubi, Yehia S. Mohamed, Mamoun Mukhtar, Akrem Elmalti, Khalid Kheirallah, Debadatta Panigrahi, Eman Y. Abu-rish, Ibrahim Bani, Eiman Mohamed Nasor, Wafa Ahmed and Abdallah Alzoubi. Hospital Mortality and Morbidity in Diabetic Patients with COVID-19: A Retrospective Analysis from the UAE. Int. J. Environ. Res. Public Health 2024, 21, 697. https://doi.org/10.3390/ ijerph21060697, International journal of environmental research and public health, Vol: 21, pp.697 - 708, May 2024
Background: Although we are four years into the pandemic, there is still conflicting evidence regarding the clinical outcomes of diabetic patients hospitalized with COVID-19. The primary objective of this study was to evaluate the in-hospital mortality and morbidity of diabetic versus nondiabetic patients hospitalized with COVID-19 in the Northern UAE Emirates. Methods: A retrospective analysis was performed on clinical data from patients with or without diabetes mellitus (DM) who were admitted to the isolation hospital with COVID-19 during the first and second waves of the disease (March 2020 to April 2021). The assessed endpoints were all-cause in-hospital mortality, length of hospitalization, intensive care unit (ICU) admission, and mechanical ventilation. Results: A total of 427 patients were included in the analysis, of whom 335 (78.5%) had DM. Compared to nondiabetics, diabetic COVID-19 patients had a significantly longer in-hospital stay (odds ratio (OR) = 2.35; 95% confidence interval (CI) = 1.19–4.62; p = 0.014), and a significantly higher frequency of ICU admission (OR = 4.50; 95% CI = 1.66–7.34; p = 0.002). The need for mechanical ventilation was not significantly different between the two groups (OR: distorted estimates; p = 0.996). Importantly, the overall in-hospital mortality was significantly higher among diabetic patients compared to their nondiabetic counterparts (OR = 2.26; 95% CI = 1.08–4.73; p = 0.03). Conclusion: DM was associated with a more arduous course of COVID-19, including a higher mortality rate, a longer overall hospital stay, and a higher frequency of ICU admission. Our results highlight the importance of DM control in COVID-19 patients to minimize the risk of detrimental clinical outcomes
About the journal
Ibrahim Bani, Yehia Mohamed, Gabriel Andrade. Evaluation of the impact of COVID-19 on stress and burnout among Ajman university (AU) medical students. Acta Psychologica 246 (2024) 104245, Acta Psychologica, Vol: 246, Apr 2024
This study was conducted at AU to estimate the prevalence of stress and burnout among medical students during the COVID-19 pandemic. This study aimed to provide insights into the levels of stress and burnout experienced by medical students at AU and identify potential risk factors. The research methodology involved a crosssectional survey using a self-administered questionnaire among 215 College of Medicine AU students. The findings indicated that many participants experienced moderate stress levels, as revealed by data collected on a Likert scale. No significant differences in stress scores were found based on sex, but variations were observed among years of study and living status. An analysis of burnout using the Copenhagen Burnout Inventory showed that over half of the participants experienced moderate levels of burnout. No significant differences in burnout were found based on gender, marital status, residence, GPA, motivation for enrolment, or nationality; however, variations were observed among different age groups and years of study. These findings highlight the need for targeted interventions and support systems to address stress and burnout among AU students by focusing on the identified risk factors. By implementing evidence-based strategies, AU can promote the well-being and resilience of medical students, thereby contributing to their overall success and the future of the healthcare workforce.
About the journal
Yehia S. Mohamed, Anastasiya Spaska , Gabriel Andrade , Mohamed A. Baraka, Hafiz Ahmad, Sinclair Steele, Eman Y. Abu-rish, Eiman Mohamed Nasor, Kowthar Forsat , Hajar Jamal Teir , Ibrahim Bani , Debadatta Panigrahi. Hand hygiene knowledge, attitude, and practice before, during and post COVID-19: a cross-sectional study among university students in the United Arab Emirates. Infection Prevention in Practice 6 (2024) 100361, Infection Prevention in Practice, Vol: 6, Mar 2024
Aims: Hand hygiene (HH) is an essential practice to evade the transmission of germs and minimize community-acquired infections. This study assesses the knowledge, attitude and practice (KAP) of HH and other health and safety measures before, during, and after the COVID-19 pandemic. in university students in the United Arab Emirates (UAE). Methods: A cross-sectional questionnaire study was conducted between December 2022 and March 2023, targeting university students from all disciplines and study levels. A 44- item questionnaire was used which included student demographics, knowledge, attitude, and practice of HH, as well as the anticipated risk of COVID-19 morbidity and mortality. Participants consented before commencing the questionnaire, and the collected data were analysed using the student’s t-test and ANOVA test, as required. Results: A total of 378 responses were received nationwide, with a valid response rate of 98%. The HH knowledge revealed an average score of 62%, which was significantly higher in students with moderate family income. Additionally, the average attitude score was 74.7%, as measured on the Likert scale, and the score lacked any correlation with the other variables. HH practice showed an average score of 86.8%, which was correlated with the students’ gender and field of study. Conclusions: This study showed a moderate level of knowledge, a good attitude, and good practice around HH and other safety measures among the UAE’s university students. Socioeconomic status, gender, and field of study influenced the study outcomes
About the journal
Mamoun Mukhtar, Yehia S. Mohamed, Murtada Elbagir, Yohannes Tesfa, Sami Kenz, Vijay Kumar, Sijomol Skaria, Mohamed A. Baraka, Ghassan Darwich, Akrem Elmalti. Vitamin B12 Status Among Patients With Type 2 Diabetes Mellitus. J Endocrinol Metab. 2024;14(1):33-39, J Endocrinol Metab, Vol: 14, Feb 2024, doi: 10.14740
Background: Vitamin (vit.) B12 is a vital nutrient for ideal hemopoietic, neurocognitive, and cardiovascular integrity. The frequency of vit. B12 abnormalities in patients with type 2 diabetes mellitus (T2DM), especially with the chronic use of metformin, has been demonstrated and verified. In this study, the levels of vit. B12 and its metabolites in metformin-using T2DM participants were measured and compared to healthy participants to conclude any causal relationship. Methods: The study was conducted on selected T2DM patients who are using a high dose of metformin for the long term and compared to healthy volunteers regarding the following parameters: body mass index (BMI), waist circumference, complete blood cell (CBC), serum homocysteine, methylmalonic acid, transcobalamin, and holotranscobalamin. SPSS was used for data analysis, implementing the unpaired Student’s t-test and the Chi-square test for significance. Results: Levels of holo-transcobalamin and homocysteine were insignificant higher in T2DM patients. However, transcobalamin was insignificantly higher in the test group, while methylmalonic acid was surprisingly below the normal levels among both groups. No significant difference in BMI was reported between both groups, but T2DM patients had significantly higher waist circumferences compared to their healthy counterparts.
About the journal
Panigrahi, D., Mohamed, Y.S., Khan, E., Panigrahi, D., Mohamed, Y.S., Khan, E. (2023). Enhancing Lecture Attendance: A Novel Approach Utilizing Clinical Case-Based Learning. Adv Mach Lear Art Inte, 4(2), 41-43., Advances in Machine Learning & Artificial Intelligence(AMLAI), Vol: 4, pp.41 - 43, Oct 2023
There has been an observable trend indicating a decline in students' attendance at lectures. Several reasons for this have been proposed, and various measures to mitigate this have been suggested in the past. We implemented a novel approach in our instructional strategy to address this. Real-life clinical problems relevant to the topic were integrated into the lectures, and they were deliberately excluded from the pre-lecture handouts. During the lectures, students were motivated to post questions and actively engage in peer-to-peer and peer-tutor discussions. To evaluate the impact of this intervention, student attendance before and after was monitored, calculated and statistically analyzed to get the average attendance. The results revealed a significant increase in the average attendance, demonstrating a statistically meaningful difference (p
About the journal
Debadatta Panigrahi, Erum Khan, Yehia Mohamed and Ashok Rattan. , Debadatta Panigrahi, Erum Khan, Yehia Mohamed and Ashok Rattan. Factors Affecting Patients Test Results". Acta Scientific Microbiology 5.10 (2022): 59-67., Act Scientific Microbiology, Vol: 5, pp.59 - 67, Sep 2022
Abstract The clinical diagnostic laboratory plays a very important role in the safe delivery of quality service to the patient. Over 70 percent of all management decisions in clinics and hospitals are based on laboratory results. It is therefore of paramount importance that the laboratory issues out reports that are accurate, reliable, reproducible and available to clinicians in a clinically relevant time frame. The diagnostic cycle can be divided into three phases (which has been further divided into five), with the pre analytical phase being the most error prone. A number of variables effect the results and each variable has to be controlled if we wish to obtain reliable results. Sensitivity and specificity are inherent attributes of a test, but the positive and negative predictive value depends upon the prevalence of the disease in the community. We can increase the value of the test by considering the likelihood ratio and understanding the purpose of the test.
About the journal
Mohamed A. Baraka, Amany Alboghdadly, Samar Alshawwa, Asim Ahmed Elnour, Hassan Alsultan, Taha Al, Hussain Alaithan, Md. Ashraful Islam, Kareem Ahmed El-Fass, Yehia Mohamed, Abdulsalam A. Alasseri and Khairi Mustafa Fahelelbum. Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences: A Cross Sectional Study in Eastern Province of Saudi Arabia. Antibiotics 2021, 10, 878. https://doi.org/10.3390/antibiotics10070878
Factors reported in the literature associated with inappropriate prescribing of antimicrobials include physicians with less experience, uncertain diagnosis, and patient caregiver influences on physicians’ decisions. Monitoring antimicrobial resistance is critical for identifying emerging resistance patterns, developing, and assessing the effectiveness of mitigation strategies. Improvement in prescribing antimicrobials would minimize the risk of resistance and, consequently, improve patients’ clinical and health outcomes. The purpose of the study is to delineate factors associated with antimicrobial resistance, describe the factors influencing prescriber’s choice during prescribing of antimicrobial, and examine factors related to consequences of inappropriate prescribing of antimicrobial. A cross-sectional study was conducted among healthcare providers (190) in six tertiary hospitals in the Eastern province of Saudi Arabia. The research panel has developed, validated, and piloted survey specific with closed-ended questions. A value of p < 0.05 was considered to be statistically significant. All data analysis was performed using the Statistical Package for Social Sciences (IBM SPSS version 23.0). 72.7% of the respondents have agreed that poor skills and knowledge are key factors that contribute to the inappropriate prescribing of antimicrobials. All of the respondents acknowledged effectiveness, previous experience with the antimicrobial, and reading scientific materials (such as books, articles, and the internet) as being key factors influencing physicians’ choice during antimicrobial prescribing. The current study has identified comprehensive education and training needs for healthcare providers about antimicrobial resistance. Using antimicrobials unnecessarily, insufficient duration of antimicrobial use, and using broad spectrum antimicrobials were reported to be common practices. Furthermore, poor skills and knowledge were a key factor that
About the journal
Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Zara Hannoun, Alison Crook, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, and Tomáš Hanke. Specificity of CD8 T-Cell Responses following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya. Vaccines 2020, 8(2), 260 https://www.mdpi.com/2076-393X/8/2/260 2
Yehia S. Mohamed, Borthwick N, Hanoon Z. Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines. BSI congress. Dec 2019. https://www.eventsforce.net/bsi/frontend/reg/absViewDocumentFE.csp?documentID=265
Wafaa S.S. Khalaf, Mamta Garg, Yehia S. Mohamed, Cordula Stover, Michael J Browning. In vitro generation of cytotoxic T cells with the potential for adoptive tumour immunotherapy of Multiple Myeloma. Frontiers Immunology. Aug. 2019; (10): 1792. https://doi.org/10.3389/fimmu.2019.01792
Eman Y. Abu-Rish, Lina A. Dahabiyeh, Yasser Bustanjia, Yehia S. Mohamed, Michael J. Browning. Effect of lamotrigine on in vivo and in vitro cytokine secretion in murine models of inflammation. Neuroimmunology. Sep. 2018; (322): 36-45. https://doi.org/10.1016/j.jneuroim.2018.06.008
Eman Y. Abu-Rish, Shada Y. Elhayek, Yehia S. Mohamed, Islam Hamad and Yasser Bustanji. Evaluation of immunomodulatory effects of lamotrigine in Balb/c mice. Acta Pharm. Sept. 2017; 67(4) https://doi.org/10.1515/acph-2017-0035
Yehia S. Mohamed, Wafaa Khalaaf and Michael Browning. APC / tumour cell hybrid vaccines in cancer immunotherapy. Immunotherapy - Myths, Reality, Ideas and Future. InTech Open access publishing, April 2017. Edited by Krassimir Metodiev, ISBN 978-953-51-3106-9. https://www.intechopen.com/books/immunotherapy-myths-reality-ideas-future
Yehia S. Mohamed, Layla A. Bashawri, Chittibabu Vatte, Cyril Cyrus, Eman Y. Abu-rish, Wafaa S. Khalaaf and Michael J. Browning. The in vitro generation of multi-tumor antigen-specific cytotoxic T cell clones: Candidates for leukemia adoptive immunotherapy following allogeneic stem cell transplantation. Molecular Immunology. Sept. 2016; (77):79–88. https://doi.org/10.1016/j.molimm.2016.07.012
Eman Y. Abu-Rish, Mohammad K. Mohammad, Mohammad M. Hudaib, Sundus Mashalla, Loay Mashallah, Violet Kasabri, Khaled Tawaha, Yehia S. Mohamed, Yasser K. Bustanji. Evaluation of the antiproliferative activity of some traditional anticancer herbal remedies from Jordan. Trop J Pharm Res, March 2016; 15(3): 469. http://dx.doi.org/10.4314/tjpr.v15i3.6
Yehia S. Mohamed and Michael Browning. Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro. Cancer Immunol Res Jan 2016; (4): B099. https://cancerimmunolres.aacrjournals.org/content/4/1_Supplement/B099
Al-Amri, Ali M., Vatte, Chittibabub; Cyrus, Cyril, Chathoth, Shahanas, Hashim, Tariq Mohammad, Yehia S. Mohamed, Ali, Rudaynah Ala, Alsaid, Abira, Ali, Amin Al. Novel mutations of the PIK3CA gene in head and neck squamous cell carcinoma. Cancer Biomarkers. Jan. 2016; 16(3) :377-383. http://DOI: 10.3233/CBM-160576
Yehia S. Mohamed. Tumor-specific cytotoxic T lymphocytes: A candidate for adoptive immunotherapy of hematological malignancies. Clin Pharmacol Biopharm. Nov 2015; 4(4); 124. DOI: 10.4172/2167-065X.C1.014 12
Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, Sarah Alderson and Michael J. Browning. In vitro evaluation of human hybrid cell lines generated by fusion of Blymphoblastoid cells and ex vivo tumour cells as candidate vaccines for haematological malignancies. Vaccine. Oct 2012; 30(46):6578-87. https://doi.org/10.1016/j.vaccine.2012.08.032 13.
Yehia S. Mohamed, Debbie Dunnion, Iryna Teobald, Renata Walewska, and Michael J. Browning. Long-lived fusions of human haematological tumour cells and B-lymphoblastoid cells induce tumour antigen-specific cytotoxic T-cell responses in vitro. Immunobiology. July 2012; 217(7):719-29. https://www.sciencedirect.com/science/article/pii/S0171298511002610
Conference Presentation
- Presented my abstract at the “Recent Advances in Primary Immuno-dysregulation Disorders (RAPID) conference which will be taking place in Sidra Medicine, Doha, Qatar, on May 9 – 10, 2024”
- Presented at the “CDC-NIH/NIAID-MBRU Joint Conference: Research and Public Health Priorities in the MENA Region, April, 26 -27th, 2024” https://www.mbru.ac.ae/cdc-niaid-joint-conference
- Recently, I presented the results of my current study on “Morbidity and mortality outcomes of Covid-19-infection in diabetic patients; a single-center retrospective study at SKMCA and Rashid Center for Diabetes and Research” in the 3RD INTERNATIONAL CONFERENCE ON MICROBIOLOGY AND IMMUNOLOGY- DUBAI- CITY SEASON- 6-7th NOV 2023 https://crgconferences.com/microbiology/
- The 6th Annual Research Competition at the AUE- Sep 11-12th 2023 at the International Academic City, Dubai. (our research team won the 1st place out of 29 competing projects in the medical discipline). https://aue.ae/6th-aue-student-research-competition-american-university-in-the-emirates/
- The Canada Immunization Conference (CIC)- Organized by Canadian Public Health Association, Ottawa, Canada. April 25- 27th, 2023 (delegate). https://www.cpha.ca/cic2023-overview
- The 2nd International Forum of Educational Mental Health (IFEMH)- Feb 23- 24th, 2023, Ajman University, UAE (organizing committee member). https://www.ajman.ac.ae/en/ifemh-2023
- The 7th International Conference of Faculty of Pharmacy- Al-Azhar University, Cairo, Egypt. 22-23 Oct 2022. Poster title: "Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences, a cross sectional study in multiple Saudi Hospitals."
- The 4th European Conference on Vaccines and Immunology- Oct 04-05, 2021- London- UK. Presentation title: “Specificity of CD8+ T-Cell Responses to HIV-1 Vaccines, Lessons for Covid-19“
- Immunology Research Focus Group (IRFG) virtual meeting- NIH-affiliated MENA region, oral presentation entitled: Understanding immune responses to improve vaccine design. March 9, 2021
- BSI Congress 2019, ACC Liverpool, UK, Dec 2-5, 2019. Presentation title: Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines.
- GCCMID2018, Gulf Congress on Clinical Microbiology and Infectious Diseases, Conrad Hotel Dubai, UAE, Nov 7-10th 2018, Poster presentation entitled “Innovative HIV-1-specific CD8 T-cell epitopes revealed in human recipients of conserved-proteome T-cell vaccine”.
- European Oncology Convention, ExCeL, London, UK, June 5-6th 2018. Attendee and workshops participant. ▪ BSI- Oxford Immunology Symposium, Mathematical Institute, Oxford University, 16-17th April 2018, Attendee and workshop participant.
- Pharma middle east conference, Dubai, UAE, Nov 2nd-4th, 2015, poster presentation entitled: Tumor-specific cytotoxic T lymphocytes; a candidate for adoptive immunotherapy of hematological malignancies.
- CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference, Translating Science into Survival, Sheraton, Times Square Hotel, New York, USA, September 16-19, 2015. Participation and poster presentation entitled: Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro.
- The University of Dammam Annual Scientific Research Update: The Medical and Biomedical research 2015; Conference hall, Dammam, KSA, April 5-7th 2015.
- Third international conference on quality assurance in postsecondary education, Sheraton Dammam Hotel, Dammam, Saudi Arabia, April 27-29th 2013
- Leicester University Postgraduate Research Festival, Leicester, UK, 16th June 2011. ▪ International Conference on “Progress in Vaccination Against Cancer” (PIVAC-10) held in St. Catharine’s College, Cambridge, UK, 27–30th September 2010. Participation and poster presentation
Presented my abstract at the “Recent Advances in Primary Immuno-dysregulation Disorders (RAPID) conference which will be taking place in Sidra Medicine, Doha, Qatar, on May 9 – 10, 2024”
Presented at the “CDC-NIH/NIAID-MBRU Joint Conference: Research and Public Health Priorities in the MENA Region, April, 26 -27th, 2024” https://www.mbru.ac.ae/cdc-niaid-joint-conference
Recently, I presented the results of my current study on “Morbidity and mortality outcomes of Covid-19-infection in diabetic patients; a single-center retrospective study at SKMCA and Rashid Center for Diabetes and Research” in the 3RD INTERNATIONAL CONFERENCE ON MICROBIOLOGY AND IMMUNOLOGY- DUBAI- CITY SEASON- 6-7th NOV 2023 https://crgconferences.com/microbiology/
The 6th Annual Research Competition at the AUE- Sep 11-12th 2023 at the International Academic City, Dubai. (our research team won the 1st place out of 29 competing projects in the medical discipline). https://aue.ae/6th-aue-student-research-competition-american-university-in-the-emirates/
The Canada Immunization Conference (CIC)- Organized by Canadian Public Health Association, Ottawa, Canada. April 25- 27th, 2023 (delegate). https://www.cpha.ca/cic2023-overview
The 2nd International Forum of Educational Mental Health (IFEMH)- Feb 23- 24th, 2023, Ajman University, UAE (organizing committee member). https://www.ajman.ac.ae/en/ifemh-2023
The 7th International Conference of Faculty of Pharmacy- Al-Azhar University, Cairo, Egypt. 22-23 Oct 2022. Poster title: "Perspectives of Healthcare Professionals Regarding Factors Associated with Antimicrobial Resistance (AMR) and Their Consequences, a cross sectional study in multiple Saudi Hospitals."
The 4th European Conference on Vaccines and Immunology- Oct 04-05, 2021- London- UK. Presentation title: “Specificity of CD8+ T-Cell Responses to HIV-1 Vaccines, Lessons for Covid-19“
Immunology Research Focus Group (IRFG) virtual meeting- NIH-affiliated MENA region, oral presentation entitled: Understanding immune responses to improve vaccine design. March 9, 2021
BSI Congress 2019, ACC Liverpool, UK, Dec 2-5, 2019. Presentation title: Mapping of HIV-1 CD8 T-cell epitopes in East African recipients of conserved-region T-cell vaccines.
GCCMID2018, Gulf Congress on Clinical Microbiology and Infectious Diseases, Conrad Hotel Dubai, UAE, Nov 7-10th 2018, Poster presentation entitled “Innovative HIV-1-specific CD8 T-cell epitopes revealed in human recipients of conserved-proteome T-cell vaccine”.
European Oncology Convention, ExCeL, London, UK, June 5-6th 2018. Attendee and workshops participant. ▪ BSI- Oxford Immunology Symposium, Mathematical Institute, Oxford University, 16-17th April 2018, Attendee and workshop participant.
Pharma middle east conference, Dubai, UAE, Nov 2nd-4th, 2015, poster presentation entitled: Tumor-specific cytotoxic T lymphocytes; a candidate for adoptive immunotherapy of hematological malignancies.
CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference, Translating Science into Survival, Sheraton, Times Square Hotel, New York, USA, September 16-19, 2015. Participation and poster presentation entitled: Immortalized HMy2/solid tumor hybridomas induce two different tumor antigen-specific T cell clones in vitro.
The University of Dammam Annual Scientific Research Update: The Medical and Biomedical research 2015; Conference hall, Dammam, KSA, April 5-7th 2015.
Third international conference on quality assurance in postsecondary education, Sheraton Dammam Hotel, Dammam, Saudi Arabia, April 27-29th 2013
Leicester University Postgraduate Research Festival, Leicester, UK, 16th June 2011. ▪ International Conference on “Progress in Vaccination Against Cancer” (PIVAC-10) held in St. Catharine’s College, Cambridge, UK, 27–30th September 2010. Participation and poster presentation
Memberships, Awards and Honors
- Highest Achiever of Faculty Continuing Professional Development (Issued by TLC of AU) as it pertains to Teaching and Learning in the College of Medicine in the academic year 2021-2022
- Medical Laboratory Professional's Association of Ontario (MLPAO), Canada. Member (Jul 2020- present).
- Canadian Society for Medical Laboratory Science (CSMLS). Member (Jul 2020- present)
- The Egyptian MoHP, Licensed Medical Laboratory Specialist (Mar 2020- present)
- Oxford University's Macrophage/ Neutrophil Research club, Member (Oct 2017- present)
- The American Association for Cancer Research (AACR), member (2015- 2016)
- The British Society for Immunology (BSI), member (Jun 2008 - present)
- The Egyptian Pharmacists Syndicate (EPS), active member (2000- present)