Contact
i.elserafi@ajman.ac.ae
06 705 5345
Ajman Campus
Ibrahim Taher Ibrahim El Serafi

  • Ibrahim Taher Ibrahim El Serafi

  • Associate Professor, Head of the Basic Medical Sciences Department
  • Ext: 5345
  • CV

Dr. Ibrahim Taher Ibraim El Serafi is an Associate Professor in the College of Medicine at Ajman University, where he teaches General Chemistry, Biochemistry, Molecular Medicine, and Clinical Biochemistry to medical students in years one through four. After graduating from the Faculty of Medicine, Suez Canal University, Egypt, Dr. El Serafi began his clinical and teaching career at the Department of Medical Biochemistry and Molecular Biology in 2004. He obtained a Master’s degree in Molecular Biology before pursuing his Ph.D. at Karolinska Institutet, Sweden, in January 2010, where he defended his thesis in the Department of Laboratory Medicine. Dr. El Serafi later joined Port-Said University, Egypt, as an Assistant Professor of Biochemistry, where he was actively involved in both clinical practice and teaching for two years. In 2017, he continued his academic career as a post-doctoral fellow at Linköping University, Sweden. He returned to Karolinska Institutet in 2018, first as a post-doctoral fellow and later as an Assistant Professor in the Department of Oncology-Pathology. His research experience spans the fields of pharmacogenomics, personalized medicine, adoptive T cell therapy, and the development of animal models. He also has extensive expertise in the development and validation of analytical methods using various analytical techniques. Dr. El Serafi is a dedicated scholar, committed to advancing scientific knowledge and improving medical practice.

Education
  • PhD, Department of Laboratory Medicine, Karolinska Institutet, Sweden, 2014.
  • Master's Degree, Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Suez Canal University, Egypt, 2007.
  • M.B.B.Ch., Faculty of Medicine, Suez Canal University, Egypt, 2002.
Experience
  • Assistant Professor, Basic Medical Sciences Department, College of Medicine, Ajman University, UAE, 2022.
  • Assistant Professor, Department of Oncology-Pathology, Karolinska Institutet, Sweden, 2019.
  • Post-doctoral Fellow, Department of Oncology-Pathology, Karolinska Institutet, Sweden, 2018.
  • Post-doctoral Fellow, Department of Clinical-Experimental Medicine, Linköping University, Sweden, 2017.
  • Assistant Professor, Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Port-Said University, Egypt, 2015.
  • Post-doctoral Fellow, Department of Laboratory Medicine, Karolinska Institutet, Sweden, 2014.
  • Ph.D. Student, Department of Laboratory Medicine, Karolinska Institutet, Sweden, 2010.
  • Assistant Lecturer, Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Suez Canal University, Egypt, 2008.
  • Demonstrator, Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Suez Canal University, Egypt, 2004.
Teaching Area
  • Molecular Medicine
  • General Chemistry
  • Basic Biochemistry
  • Clinical Biochemistry
Research
  • Adoptive T cell therapy
  • Personalized medicine on pharmacogenomics bases
  • Hematopoietic stem cell transplantation
  • Stem cell therapy for skin regeneration
  • Hematological malignancies
  • Animal models
Publications
Conference Presentation
  • "Mechanisms Underlying Seizures and Hypothermia During Busulfan Administration," Poster Presentation at the 29th Congress of the European Hematology Association (EHA), June 13-16, 2024, Madrid, Spain.
  • "Tumor-Tailored Lymphodepletion and CAR T-Cell Functionality in Advanced Ovarian Cancer," Poster Presentation at the 2nd Translational Research Conference: Immune & Cellular Therapies - Focus on Advanced Gene-Engineered Immune Cells, organized by The European School of Hematology (ESH), September 12-14, 2022, Berlin, Germany.
  • "Mesothelin-Directed Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Advanced Ovarian Cancer," Poster Presentation at The International Conference on Immune and Cellular Therapies: Focus on Immune-Based Therapeutic Concepts, organized by The European School of Hematology (ESH), September 20-22, 2019, Mandelieu, France.
  • "Immunotherapy for Cancer Treatment," Plenary Speaker at the Recent Advances in Molecular and Cellular Medicine, the Center of Excellence in Molecular and Cellular Medicine Second Annual Conference, Faculty of Medicine, Suez Canal University, December 26-27, 2018, Ismailia, Egypt.
  • "The Establishment of Ovarian Cancer Mouse Model for the Evaluation of MSLN CAR T-Cells," Oral Presentation at Kick-Off 2018, Oncology-Pathology Department, Karolinska Institutet, August 29th, 2018, Stockholm, Sweden.
  • "Pre-Analytical Investigations for Establishing a Protocol for Treosulfan Handling and Activation," Abstract at the 23rd Congress of the European Hematology Association (EHA), June 14-17, 2018, Stockholm, Sweden.
  • "Reduced Risk of Sinusoidal Obstruction Syndrome of the Liver After Bu-Cy Conditioning Before Allogeneic Hematopoietic Stem Cell Transplantation: A Result of Personalized Dose Adjustment," Abstract at the 23rd Congress of the European Hematology Association (EHA), June 14-17, 2018, Stockholm, Sweden.
  • "The Effect of N-Acetyl-L-Cysteine (NAC) on Liver Toxicity and Clinical Outcome After Hematopoietic Stem Cell Transplantation," Oral Presentation at The International Hematologists Summit, May 21-22, 2018, Valencia, Spain.
  • "Characterization of MSLN CAR T-Cells in an Ovarian Cancer Model," Poster Presentation at Frontiers in Cancer Research and Therapy, March 8-9, 2018, Stockholm, Sweden.
  • "Vitamin D Relation to Busulfan in Pediatrics Undergoing Hematopoietic Stem Cell Transplantation," Abstract at The American Society of Hematology (ASH) 59th Annual Meeting and Exposition, December 9-12, 2017, Atlanta, GA, USA.
  • "Biodistribution of Busulfan Metabolites and Their Effect on the Central Nervous System," Poster Presentation at the 23rd Mayo Clinic-Karolinska Institutet Annual Scientific Research Meeting, September 7-8, 2017, Stockholm, Sweden.
  • "Toxicological Side-Effects of Fludarabine and Treosulfan Conditioning Before Allogeneic Stem-Cell Transplantation," Poster Presentation at the 43rd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), March 26-29, 2017, Marseille, France.
  • "Towards Personalized Medicine on Pharmacogenomics Basis," Oral Presentation at the 1st Annual Conference of the Faculty of Medicine, Port-Said University, March 24-25, 2016, Port-Said, Egypt.
  • "The Importance of Pharmacogenomics in Personalized Conditioning Regimen Prior to Stem Cell Transplantation," Oral Presentation at the 1st Annual Biomedical Conference, Recent Advances in Stem Cell Research, Faculty of Medicine, Suez Canal University, October 29-30, 2015, Ismailia, Egypt.
  • "Busulfan Metabolism via Flavin-Containing Monooxygenase 3 (FMO3) Can Explain Several Interactions with Other Drugs," Poster Presentation at the 56th American Society of Hematology (ASH) Annual Meeting and Exposition, December 6-9, 2014, San Francisco, CA, USA.
  • "The Role of CYP2J2 in Cyclophosphamide Metabolism," Poster Presentation at the 18th Congress of the European Hematology Association (EHA), June 13-16, 2013, Stockholm, Sweden.
  • "Microbubbles and Microcapsules as Drug Delivery Vehicles for Chemotherapy," Poster Presentation at the Label-Free Technologies Conference, Advances and Applications, November 1-3, 2012, Amsterdam, Netherlands.
  • "The Role of Human CYP2B6 Polymorphism and Reductase on Bioactivation of Cyclophosphamide," Invited Speaker at the 17th Congress of the European Hematology Association (EHA), June 14-18, 2012, Amsterdam, Netherlands.
  • "Molecular Analysis of Possible Mutations in the Gamma Globin Gene in Patients with Beta Thalassemia in the Suez Canal Region," Oral Presentation at the 5th Scientific Congress of the Clinical Pathology Department, Faculty of Medicine, Suez Canal University, May 2007, Ismailia, Egypt.
Memberships, Awards and Honors
  • Certificate of Appreciation, Ajman University, UAE, 2024.
  • Certificate of Recognition, Ajman Municipality and Planning Department, UAE, 2023.
  • Declaration of Honor from the Center of Excellence in Molecular and Cellular Medicine, Faculty of Medicine, Suez Canal University, Egypt, 2018.
  • Swedish Medical Association (SLS), 2017.
  • European Hematology Association (EHA), 2012.