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Abdallah Adel Damen Alzoubi
- Associate Professor, Head of Pathological Sciences Department
- Ext: 5340
Dr. Abdallah Alzoubi is an Associate Professor of Pharmacology, Head of Pathological Sciences Department, and Director of Phase II of the Pre-Clerkship Program at the College of Medicine, Ajman University. He holds an MD degree from the School of Medicine at Jordan University of Science and Technology (JUST), Jordan (2005), and a PhD degree in Clinical Pharmacology from the University of South Alabama, United States of America (2013). Dr. Alzoubi previously served as an Associate Professor and Chairman of Pharmacology and as an Assistant Dean for Basic Medical Sciences Affairs at the School of Medicine, JUST. During those appointments, he was actively involved in committees for the continuous assessment and evolution of medical education and curriculum development, and coordinated the most recent updates of curriculum of graduate studies in Basic Medical Sciences, at the School of Medicine. Dr. Alzoubi has approximately 30 publications in internationally indexed journals, with research interests in the fields of cardiopulmonary diseases, endocrine disorders, and tobacco delivery systems. He is adept in research design and methodology, ranging from pre-clinical in vitro and in vivo approaches, to clinical trials and epidemiological studies, and holds several grants to fund his research activities. Dr. Alzoubi continues to serve as a reviewer for many local, regional, and international medical Journals and funding agencies.
Education
- MD; Jordan University of Science and Technology, Jordan, 2005
- PhD, University of South Alabama, USA, 2013
MD; Jordan University of Science and Technology, Jordan, 2005
PhD, University of South Alabama, USA, 2013
Experience
- Head of the Department of Pathological Sciences; Director of Phase II of the Medical Curriculum, College of Medicine, Ajman University
- Associate Professor, Dept. of Pharmacology, School of Medicine, Jordan University of Science and Technology, 2 years
- Chairperson of Pharmacology, School of Medicine, Jordan University of Science and Technology, 3 years
- Assistant Dean for Basic Medical Sciences Affairs, School of Medicine, Jordan University of Science and Technology, 3 years
- Director, International Relations Office, Jordan University of Science and Technology, 3 years
- Academic Coordinator, Joint Medicine Program, Xavier University School of Medicine and Jordan University of Science and Technology, Jordan, 2 years
- Member, Drug Licensing Committee, Jordanian Food and Drug Administration (JFDA), Jordan, 1 year
Head of the Department of Pathological Sciences; Director of Phase II of the Medical Curriculum, College of Medicine, Ajman University
Associate Professor, Dept. of Pharmacology, School of Medicine, Jordan University of Science and Technology, 2 years
Chairperson of Pharmacology, School of Medicine, Jordan University of Science and Technology, 3 years
Assistant Dean for Basic Medical Sciences Affairs, School of Medicine, Jordan University of Science and Technology, 3 years
Director, International Relations Office, Jordan University of Science and Technology, 3 years
Academic Coordinator, Joint Medicine Program, Xavier University School of Medicine and Jordan University of Science and Technology, Jordan, 2 years
Member, Drug Licensing Committee, Jordanian Food and Drug Administration (JFDA), Jordan, 1 year
Teaching Area
- Clinical Pharmacology
Clinical Pharmacology
Research
- Pulmonary arterial hypertension and heart failure; pre-clinical models, pathophysiology, and treatment
- Metabolic syndrome; pathophysiology and treatment
- Tobacco delivery systems; epidemiological correlates, hazards, and preventive measures
Pulmonary arterial hypertension and heart failure; pre-clinical models, pathophysiology, and treatment
Metabolic syndrome; pathophysiology and treatment
Tobacco delivery systems; epidemiological correlates, hazards, and preventive measures
Publications
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Alzoubi A, Kanaan H, Alhazaimeh D, Gharaibeh S, Mukattash TL, Kheirallah K. Knowledge, attitude, future expectations and perceived barriers of medical students and physicians regarding pharmacogenomics in Jordan. Int J Clin Pract. 2020 Aug 9:e13658. doi: 10.1111/ijcp.13658.
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Khassawneh AH, Alzoubi A, Khasawneh AG, Abdo N, Abu-Naser D, Al-Mistarehi AH, Albattah MF, Kheirallah KA. The relationship between depression and metabolic control parameters in type 2 diabetic patients: A cross-sectional and feasibility interventional study. Int J Clin Pract. 2020 Oct 23:e13777. doi: 10.1111/ijcp.13777
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Kheirallah KA, Alsinglawi B, Alzoubi A, Saidan MN, Mubin O, Alorjani MS, Mzayek F. The Effect of Strict State Measures on the Epidemiologic Curve of COVID-19 Infection in the Context of a Developing Country: A Simulation from Jordan. Int J Environ Res Public Health. 2020 Sep 8;17(18):E6530. doi: 10.3390/ijerph17186530.
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Kheirallah KA, Abdulrazeq F, Alzoubi A, Alsulaiman JW, Alrabadi N, Alfaqih MA, Al Zoubi MS, Matsumoto MM. Stem Cell-Related Knowledge and Attitudes among Physicians in Jordan. Int J Clin Pract. 2021 Mar 8:e14142. doi: 10.1111/ijcp.14142. Online ahead of print. PMID: 33682227
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Kheirallah KA, Cobb CO, Alsulaiman JW, Alzoubi A, Hoetger C, Kliewer W, Mzayek F. Trauma exposure, mental health and tobacco use among vulnerable Syrian refugee youth in Jordan. J Public Health (Oxf). 2019 Nov 20. pii: fdz128. doi: 10.1093/pubmed/fdz128.
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Mazahreh TS, Alfaqih M, Saadeh R, Al-Zoubi NA, Hatamleh M, Alqudah A, Aleshawi AJ, Alzoubi A. The Effects of Laparoscopic Sleeve Gastrectomy on the Parameters of Leptin Resistance in Obesity. Biomolecules. 2019 Sep 25;9(10). pii: E533. doi: 10.3390/biom9100533.
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Aljarrah Q, Al-Omari MH, Elheis M, Al-Jarrah M, Jamal A, Alzoubi A. Successful reversal of isolated delayed spinal cord ischemia following endovascular abdominal aneurysm repair. Vasc Health Risk Manag. 2019 Apr 23;15:81-87. doi: 10.2147/VHRM.S191197. eCollection 2019.
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Al Bashir S, Alzoubi A, Alfaqih MA, Kheirallah K, Smairat A, Haddad H, Al-Dwairy A, Fawwaz BAB, Alzoubi M, Trpkov K. PTEN Loss in a Prostate Cancer Cohort From Jordan. Appl Immunohistochem Mol Morphol. 2019 Jan 4. doi: 10.1097/PAI.0000000000000732. [Epub ahead of print]. PMID: 30614821.
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Alzoubi A, Ghazwi R, Alzoubi K, Alqudah M, Kheirallah KA, Khabour O, Allouh M. Vascular Endothelial Growth Factor Receptor Inhibition Enhances COPD Picture in Mice Exposed to Waterpipe Smoke. Folia Morphol (Warsz). 2018 Jan 3. doi: 10.5603/FM.a2017.0120. [Epub ahead of print] PMID: 29297179.
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Alzoubi A, Abunaser R, Khassawneh A, Alfaqih M, Khasawneh A, Abdo N. The Bidirectional Relationship between Diabetes and Depression: A Literature Review. Korean J Fam Med. 2018 May;39(3):137-146. doi: 10.4082/kjfm.2018.39.3.137. Epub 2018 May 18. Review.
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Alfaqih M, Khader Y, Al-Dwairi A, Alzoubi A, Al-Shboul O, Hatim A. Lower levels of serum adiponectin and the T allele of rs1501299 of the ADIPOQ gene are protective against polycystic ovarian syndrome in Jordan. Korean J Fam Med. 2018 Mar;39(2):108-113. doi: 10.4082/kjfm.2018.39.2.108. Epub 2018 Mar 22.
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Alzoubi A, Mahdi H, Bashir S. Al, Halalsheh O, Ebbini M Al, Alzarir M, Al-Ahmar K, Alfaqih M, Al-Hadidi AH. Normalization of Serum Vitamin D Improves Semen Motility Parameters in Patients with Idiopathic Male Infertility. Acta Endo (Buc), 2017. 13: 201-208 doi: 10.4183/aeb.2017.X1.
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Alqudah M, Qandeel H, Al-Zoubi N, Alqudah A, Bani-Ahmad M, Alzoubi A. Changes of serum growth factors profiles in patients with venous thromboembolism. Scand J Clin Lab Invest. 2017 Sep 26:1-6. doi: 10.1080/00365513.2017.1379607. [Epub ahead of print] PMID: 28949256.
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Kheirallah, K. A., Veeranki, S. P., Alzyoud, S., Alzoubi, A., Walker, L., Khader, Y., Mzayek, F., Ward, K. D. Collision of waterpipe and cigarette smoking epidemics among youth in Arab countries. Journal of Substance Use, 2016. 1-7. doi: 10.3109/14659891.2015.1082159.
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Alzoubi A. The Discovery of the Pulmonary Circulation; A Debate Spanning Centuries. Pulmonary Vascular Research Institute Chronicle. 2015 Jan. 2(1).
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Rawat DK*, Alzoubi A*, Gupte R, Chettimada S, Watanabe M, Kahn AG, Okada T, McMurtry IF, Gupte SA. Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension-Induced Ventricular Hypertrophy and Diastolic Heart Failure. Hypertension. 2014 Sep 29. pii: HYPERTENSIONAHA.114.03261. [Epub ahead of print].
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Chettimada S, Joshi SR, Alzoubi A, Gebb SA, McMurtry IF, Gupte RS, Gupte SA. Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L545-56. doi: 10.1152/ajplung.00303.2013. Epub 2014 Jul 25.
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Toba M, Alzoubi A, O’Neill K, Abe K, Urakami T, Komatsu M, Alvarez D, Järvinen TAH, Mann D, Ruoslahti E, McMurtry IF, Oka M. A Novel Strategy to Selectively Enhance Pulmonary Drug Efficacy in Pulmonary Hypertension. Am J Physiol Heart Circ Physiol. 2014 Jan;306(2):H243-50. doi: 10.1152/ajpheart.00728.2013. Epub 2013 Nov 15.
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Toba M, Alzoubi A, O’Neill K, Gairhe S, Matsumoto Y, Oshima K, Abe K, McMurtry IF, Oka M. Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats. Am J Physiol Heart Circ Physiol. 2013 Nov 15.
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Alzoubi A, Almalouf P, Toba M, O'Neill K, Qian X, Francis M, Taylor MS, Alexeyev M, McMurtry IF, Oka M, Stevens T. TRPC4 Inactivation Confers a Survival Benefit in Severe Pulmonary Arterial Hypertension. Am J Pathol. 2013 Oct 7. doi:pii: S0002-9440(13)00602-0. 10.1016/j.ajpath.2013.08.016. [Epub ahead of print].
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Austin ED*, Lahm T*, West J*, Tofovic SP*, Johansen AK*, MacLean MR*, Alzoubi A*, Oka M*. Gender, Sex Hormones, and Pulmonary Hypertension. Pulm Circ. 2013 Apr;3(2):294-314.
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Alzoubi A, Toba M, Abe K, O'Neill KD, Rocic P, Fagan KA, McMurtry IF, Oka M. Dehydroepiandrosterone Restores Right Ventricular Structure and Function in Rats with Severe Pulmonary Arterial Hypertension. Am J Physiol Heart Circ Physiol. 2013 Jun 15;304(12):H1708-18. doi: 10.1152/ajpheart.00746.2012. Epub 2013 Apr 12.
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Abe K, Toba M, Alzoubi A, Koubsky K, Ito M, Ota H, Gairhe S, Gerthoffer WT, Fagan KA, McMurtry IF, Oka M. Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in rats. Am J Respir Cell Mol Biol. 2011 Oct;45(4):804-8. doi: 10.1165/rcmb.2010-0371OC. Epub 2011 Mar 4.
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Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, Voelkel NF, McMurtry IF, Oka M. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation. 2010 Jun 29;121(25):2747-54. doi: 10.1161/CIRCULATIONAHA.109.927681. Epub 2010 Jun 14.
Alzoubi A, Kanaan H, Alhazaimeh D, Gharaibeh S, Mukattash TL, Kheirallah K. Knowledge, attitude, future expectations and perceived barriers of medical students and physicians regarding pharmacogenomics in Jordan. Int J Clin Pract. 2020 Aug 9:e13658. doi: 10.1111/ijcp.13658.
Khassawneh AH, Alzoubi A, Khasawneh AG, Abdo N, Abu-Naser D, Al-Mistarehi AH, Albattah MF, Kheirallah KA. The relationship between depression and metabolic control parameters in type 2 diabetic patients: A cross-sectional and feasibility interventional study. Int J Clin Pract. 2020 Oct 23:e13777. doi: 10.1111/ijcp.13777
Kheirallah KA, Alsinglawi B, Alzoubi A, Saidan MN, Mubin O, Alorjani MS, Mzayek F. The Effect of Strict State Measures on the Epidemiologic Curve of COVID-19 Infection in the Context of a Developing Country: A Simulation from Jordan. Int J Environ Res Public Health. 2020 Sep 8;17(18):E6530. doi: 10.3390/ijerph17186530.
Kheirallah KA, Abdulrazeq F, Alzoubi A, Alsulaiman JW, Alrabadi N, Alfaqih MA, Al Zoubi MS, Matsumoto MM. Stem Cell-Related Knowledge and Attitudes among Physicians in Jordan. Int J Clin Pract. 2021 Mar 8:e14142. doi: 10.1111/ijcp.14142. Online ahead of print. PMID: 33682227
Kheirallah KA, Cobb CO, Alsulaiman JW, Alzoubi A, Hoetger C, Kliewer W, Mzayek F. Trauma exposure, mental health and tobacco use among vulnerable Syrian refugee youth in Jordan. J Public Health (Oxf). 2019 Nov 20. pii: fdz128. doi: 10.1093/pubmed/fdz128.
Mazahreh TS, Alfaqih M, Saadeh R, Al-Zoubi NA, Hatamleh M, Alqudah A, Aleshawi AJ, Alzoubi A. The Effects of Laparoscopic Sleeve Gastrectomy on the Parameters of Leptin Resistance in Obesity. Biomolecules. 2019 Sep 25;9(10). pii: E533. doi: 10.3390/biom9100533.
Aljarrah Q, Al-Omari MH, Elheis M, Al-Jarrah M, Jamal A, Alzoubi A. Successful reversal of isolated delayed spinal cord ischemia following endovascular abdominal aneurysm repair. Vasc Health Risk Manag. 2019 Apr 23;15:81-87. doi: 10.2147/VHRM.S191197. eCollection 2019.
Al Bashir S, Alzoubi A, Alfaqih MA, Kheirallah K, Smairat A, Haddad H, Al-Dwairy A, Fawwaz BAB, Alzoubi M, Trpkov K. PTEN Loss in a Prostate Cancer Cohort From Jordan. Appl Immunohistochem Mol Morphol. 2019 Jan 4. doi: 10.1097/PAI.0000000000000732. [Epub ahead of print]. PMID: 30614821.
Alzoubi A, Ghazwi R, Alzoubi K, Alqudah M, Kheirallah KA, Khabour O, Allouh M. Vascular Endothelial Growth Factor Receptor Inhibition Enhances COPD Picture in Mice Exposed to Waterpipe Smoke. Folia Morphol (Warsz). 2018 Jan 3. doi: 10.5603/FM.a2017.0120. [Epub ahead of print] PMID: 29297179.
Alzoubi A, Abunaser R, Khassawneh A, Alfaqih M, Khasawneh A, Abdo N. The Bidirectional Relationship between Diabetes and Depression: A Literature Review. Korean J Fam Med. 2018 May;39(3):137-146. doi: 10.4082/kjfm.2018.39.3.137. Epub 2018 May 18. Review.
Alfaqih M, Khader Y, Al-Dwairi A, Alzoubi A, Al-Shboul O, Hatim A. Lower levels of serum adiponectin and the T allele of rs1501299 of the ADIPOQ gene are protective against polycystic ovarian syndrome in Jordan. Korean J Fam Med. 2018 Mar;39(2):108-113. doi: 10.4082/kjfm.2018.39.2.108. Epub 2018 Mar 22.
Alzoubi A, Mahdi H, Bashir S. Al, Halalsheh O, Ebbini M Al, Alzarir M, Al-Ahmar K, Alfaqih M, Al-Hadidi AH. Normalization of Serum Vitamin D Improves Semen Motility Parameters in Patients with Idiopathic Male Infertility. Acta Endo (Buc), 2017. 13: 201-208 doi: 10.4183/aeb.2017.X1.
Alqudah M, Qandeel H, Al-Zoubi N, Alqudah A, Bani-Ahmad M, Alzoubi A. Changes of serum growth factors profiles in patients with venous thromboembolism. Scand J Clin Lab Invest. 2017 Sep 26:1-6. doi: 10.1080/00365513.2017.1379607. [Epub ahead of print] PMID: 28949256.
Kheirallah, K. A., Veeranki, S. P., Alzyoud, S., Alzoubi, A., Walker, L., Khader, Y., Mzayek, F., Ward, K. D. Collision of waterpipe and cigarette smoking epidemics among youth in Arab countries. Journal of Substance Use, 2016. 1-7. doi: 10.3109/14659891.2015.1082159.
Alzoubi A. The Discovery of the Pulmonary Circulation; A Debate Spanning Centuries. Pulmonary Vascular Research Institute Chronicle. 2015 Jan. 2(1).
Rawat DK*, Alzoubi A*, Gupte R, Chettimada S, Watanabe M, Kahn AG, Okada T, McMurtry IF, Gupte SA. Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension-Induced Ventricular Hypertrophy and Diastolic Heart Failure. Hypertension. 2014 Sep 29. pii: HYPERTENSIONAHA.114.03261. [Epub ahead of print].
Chettimada S, Joshi SR, Alzoubi A, Gebb SA, McMurtry IF, Gupte RS, Gupte SA. Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L545-56. doi: 10.1152/ajplung.00303.2013. Epub 2014 Jul 25.
Toba M, Alzoubi A, O’Neill K, Abe K, Urakami T, Komatsu M, Alvarez D, Järvinen TAH, Mann D, Ruoslahti E, McMurtry IF, Oka M. A Novel Strategy to Selectively Enhance Pulmonary Drug Efficacy in Pulmonary Hypertension. Am J Physiol Heart Circ Physiol. 2014 Jan;306(2):H243-50. doi: 10.1152/ajpheart.00728.2013. Epub 2013 Nov 15.
Toba M, Alzoubi A, O’Neill K, Gairhe S, Matsumoto Y, Oshima K, Abe K, McMurtry IF, Oka M. Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats. Am J Physiol Heart Circ Physiol. 2013 Nov 15.
Alzoubi A, Almalouf P, Toba M, O'Neill K, Qian X, Francis M, Taylor MS, Alexeyev M, McMurtry IF, Oka M, Stevens T. TRPC4 Inactivation Confers a Survival Benefit in Severe Pulmonary Arterial Hypertension. Am J Pathol. 2013 Oct 7. doi:pii: S0002-9440(13)00602-0. 10.1016/j.ajpath.2013.08.016. [Epub ahead of print].
Austin ED*, Lahm T*, West J*, Tofovic SP*, Johansen AK*, MacLean MR*, Alzoubi A*, Oka M*. Gender, Sex Hormones, and Pulmonary Hypertension. Pulm Circ. 2013 Apr;3(2):294-314.
Alzoubi A, Toba M, Abe K, O'Neill KD, Rocic P, Fagan KA, McMurtry IF, Oka M. Dehydroepiandrosterone Restores Right Ventricular Structure and Function in Rats with Severe Pulmonary Arterial Hypertension. Am J Physiol Heart Circ Physiol. 2013 Jun 15;304(12):H1708-18. doi: 10.1152/ajpheart.00746.2012. Epub 2013 Apr 12.
Abe K, Toba M, Alzoubi A, Koubsky K, Ito M, Ota H, Gairhe S, Gerthoffer WT, Fagan KA, McMurtry IF, Oka M. Tyrosine kinase inhibitors are potent acute pulmonary vasodilators in rats. Am J Respir Cell Mol Biol. 2011 Oct;45(4):804-8. doi: 10.1165/rcmb.2010-0371OC. Epub 2011 Mar 4.
Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, Voelkel NF, McMurtry IF, Oka M. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation. 2010 Jun 29;121(25):2747-54. doi: 10.1161/CIRCULATIONAHA.109.927681. Epub 2010 Jun 14.
Memberships, Awards and Honors
- Member; American Thoracic Society
- Member; American Heart Association
- The Jordanian Medical Association
- Faculty of 1000 in Pharmacology membership
- Member, the Editorial Board of the Korean Journal of Family Medicine
- Member, the Editorial Board of Annals of Vascular Medicine and Research Journal
- May 2014: Travel Award and Conference Honorarium for Best Abstract. The Seventh Annual Joint Meeting of the Saudi Association for Pulmonary Hypertension and Pulmonary Vascular Research Institute, Muscat, Oman
- Fall 2009: The Edwin R. Hughes Memorial Award in Basic Medical Sciences – Outstanding Student, Class of 2008-2009, University of South Alabama, Mobile-Alabama, USA