This 4-credit hour, semester-long course integrates the basic aspects of Immunology, Microbiology, Pathology, and Pharmacology. Although several aspects are peculiar to each individual discipline, integration will be sought whenever possible to present the students with a homogeneous view of the different aspects constituting the basic mechanism of diseases essential to approach the clinical practice. Several interactive occasions in the form of Problem Based Learning (PBL), Tutorials, Assignments and Virtual Labs in Microbiology, Immunology, Pathology and Pharmacology will be implemented.