I am graduated from Faculty of Dentistry, Mansoura University, Egypt in 1990 and ranked the first. I got Master degree in conservative dentistry from the same university in 1996. I got PhD in Endodontic in 2002 from Mainz University. I worked in Mansoura university as assistant professor in 2002-2004 then worked in different hospitals in gulf areas endodontic consultant . I joined Ajman university in 2005 and now I am worked as Associate professor of endodontic in the Master restorative program. My research interest is related to endodontic branch particularly new obturation materials. My clinical work is related to microscopic endodontic treatment using surgical microscope.
logo International Journal of Dentistry + Journal Menu PDF Article Sections Research Article | Open Access Volume 2021 |Article ID 6550054 | https://doi.org/10.1155/2021/6550054 Show citation Comparing the Antifungal Effect of Sodium Hypochlorite Gel versus Different Types of Root Canal Medicaments at Different Time Intervals Using the Agar Diffusion Test: An In Vitro Study Mohamed El Sayed ,1,2 Nikta Ghanerad ,1 Zeinab Shabanpour ,1 Mahin Shabanpoor ,1 and Fatemeh Rahimi 1 Show more Academic Editor: Cesar Rogério Pucci Published 13 Dec 2021 Abstract Aims. The purpose of this study was to compare the antifungal activity of sodium hypochlorite gel to those of four intracanal medicaments at various time intervals. Materials and Methods. The agar well diffusion technique was utilized to test the antifungal activity of the following medicaments against Candida albinans (C. albicans): sodium hypochlorite gel, chlorhexidine gel, calcium hydroxide paste, Ledermix, and Diapex Plus. The inhibition zone related to each medicine was measured in millimeter after 24, 48, and 72 hours of incubation at 37°C. The data were analyzed using one-way ANOVA and Games–Howell tests, at a significance level of . Results. Except for Ledermix and Diapex Plus, which had no antifungal action, all of the medicaments showed varied inhibitory zones for C. albicans. At all periods, the NaOCl gel had the most significant inhibition zones, followed by the CHX gel and calcium hydroxide. At all time intervals, the NaOCl gel demonstrated comparable antifungal efficacy. When compared to a 24-hour time interval, the CHX gel showed an increased antifungal activity at the 48-hour and 72-hour intervals. Calcium hydroxide, on the other hand, showed a decrease in its antifungal activity at the 72-hour interval. Conclusion. The antifungal activity of sodium hypochlorite gel was the highest among the investigated medicaments. Chlorhexidine gel's antifungal activity improved over time, whereas calcium hydroxide's antifungal activity declined. Diapex Plus and Ledermix did not have any antifungal properties.