The oral microbiological environment is a key determinant in caries formation, periodontal diseases, and other oral health issues. Microbiology, the study of microorganisms including bacteria, fungi, and viruses, with emphasis on applications relevant to the study of dentistry. This course is designed to introduce the students to the microbe’s world exemplified by prokaryotes, eukaryotes, and the unique properties of the viruses. The course covers aspects of medical organisms that can inflict damages to human health in general and put some emphasis on Dental caries, Periodontal diseases, and salivary gland infections. It also covers the basic concepts of immunology, the basic concepts of sterilization & disinfection, antibiotics, and their mechanism of action to avoid the emergence of drug resistance. The above-mentioned topics give the students enough background in microbiology to prepare them with other disciplines to become professional dentists competent to work in hospitals and private clinics.